Results 11 to 20 of about 305,789 (330)
Viruses, 2022 Dengue virus replicates its single-stranded RNA genome in membrane-bound complexes formed on the endoplasmic reticulum, where viral non-structural proteins (NS) and RNA co-localize.
Satyamurthy Kundharapu +1 more
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Structural basis of the T4 bacteriophage primosome assembly and primer synthesis
Nature Communications, 2023 The T4 bacteriophage gp41 helicase and gp61 primase assemble into a primosome to couple DNA unwinding with RNA primer synthesis for DNA replication. How the primosome is assembled and how the primer length is defined are unclear.
Xiang Feng +4 more
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The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity
iScience, 2020 Summary: Members of the DEAD-box helicase family are involved in all fundamental processes of RNA metabolism, and as such, their malfunction is associated with various diseases.
Maria J. Marcaida +8 more
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HrpA, an RNA helicase involved in RNA processing, is required for mouse infectivity and tick transmission of the Lyme disease spirochete. [PDF]
PLoS Pathogens, 2013 The Lyme disease spirochete Borrelia burgdorferi must differentially express genes and proteins in order to survive in and transit between its tick vector and vertebrate reservoir. The putative DEAH-box RNA helicase, HrpA, has been recently identified as
Aydan Salman-Dilgimen +4 more
doaj +1 more source
RNA helicase domains of viral origin in proteins of insect retrotransposons: possible source for evolutionary advantages [PDF]
PeerJ, 2017 Recently, a novel phenomenon of horizontal gene transfer of helicase-encoding sequence from positive-stranded RNA viruses to LINE transposons in insect genomes was described.
Sergey Y. Morozov +2 more
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Virologica Sinica, 2020 The ongoing outbreak of Coronavirus Disease 2019 (COVID-19) has become a global public health emergency. SARS-coronavirus-2 (SARS-CoV-2), the causative pathogen of COVID-19, is a positive-sense single-stranded RNA virus belonging to the family ...
T. Shu +10 more
semanticscholar +1 more source
The EuroBiotech Journal, 2022 The pathogenic RNA virus that infects human beings contains the RNA helicase enzyme, responsible for the replication of the viral genome. The enzyme is used as a suitable target against which the drug molecule acts.
Satpathy R, Acharya S
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Identification of Five Putative Yeast RNA Helicase Genes [PDF]
, 1990 The RNA helicase gene family encodes a group of eight homologous proteins that share regions of sequence similarity. This group of evolutionarily conserved proteins presumably all utilize ATP (or some other nucleoside triphosphate) as an energy source ...
Abelson, John +2 more
core +1 more source
Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera [PDF]
, 2013 DEAD box helicases catalyze the ATP-dependent destabilization of RNA duplexes. Whereas duplex separation is mediated by the helicase core shared by all members of the family, flanking domains often contribute to binding of the RNA substrate.
Klostermeier, Dagmar +5 more
core +1 more source
The RNA helicase A in malignant transformation
OncoTarget, 2016 The RNA helicase A (RHA) is involved in several steps of RNA metabolism, such as RNA processing, cellular transit of viral molecules, ribosome assembly, regulation of transcription and translation of specific mRNAs. RHA is a multifunctional protein whose
M. Fidaleo, E. de Paola, M. Paronetto
semanticscholar +1 more source