Results 241 to 250 of about 125,618 (325)

Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls

American Journal of Medical Genetics Part A, Volume 197, Issue 8, August 2025.
ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe, Jessica Connors, Angela Arra, Katherine Dunn, Kim Blake, Johan van Limbergen   +5 more
wiley   +1 more source

RNA Helicase Vasa as a Multifunctional Conservative Regulator of Gametogenesis in Eukaryotes. [PDF]

Curr Issues Mol Biol, 2023
Adashev VE, Kotov AA, Olenina LV.
europepmc   +1 more source

A new twist on RNA helicases: DExH/D box proteins as RNPases. [PDF]

, 2001
Beate Schwer
openalex   +1 more source

Improvement of the Anticancer Efficacy of PD‐1/PD‐L1 Blockade: Advances in Molecular Mechanisms and Therapeutic Strategies

MedComm, Volume 6, Issue 8, August 2025.
Mechanisms of alleviating resistance to PD‐1/PD‐L1 blockade by IFN‐α and IFN‐β. In these mechanisms, the “yin‐yang balance” is disrupted, thus preventing T cells from attacking cancer cells. Restoring this balance may improve the efficacy of anti‐PD‐1/PD‐L1 therapy and reinvigorate T cells and other immune cells to target and destroy cancer cells ...
Peng Gao, Xiao Li, Zhenyu Duan, Yang Wang, Yinggang Li, Jing Wang, Kui Luo, Jie Chen   +7 more
wiley   +1 more source

Critical Cellular Functions and Mechanisms of Action of the RNA Helicase UAP56. [PDF]

J Mol Biol
Yellamaty R, Sharma S.
europepmc   +1 more source

A DEAD-box RNA helicase mediates meiotic silencing by unpaired DNA. [PDF]

G3 (Bethesda), 2023
Sy VT, Boone EC, Xiao H, Vierling MM, Schmitz SF, Ung Q, Trawick SS, Hammond TM, Shiu PKT.   +8 more
europepmc   +1 more source

The quest for the best target genes for RNAi‐mediated pest control

Insect Molecular Biology, Volume 34, Issue 4, Page 505-517, August 2025.
A major challenge for RNAi mediated pest control is the identification of the most effective RNAi target genes from the pool of ~37% of all genes that are essential. Effective RNAi target genes are predominantly highly conserved genes serving basic cellular functions such as protein degradation.
Doga Cedden, Gregor Bucher
wiley   +1 more source

Intrinsically disordered regions regulate RhlE RNA helicase functions in bacteria. [PDF]

Nucleic Acids Res
Hausmann S, Geiser J, Allen GE, Geslain SAM, Valentini M.   +4 more
europepmc   +1 more source

The DEAD-box RNA helicase RhlB is required for efficient RNA processing at low temperature in Caulobacter. [PDF]

Microbiol Spectr, 2023
de Araújo HL, Picinato BA, Lorenzetti APR, Muthunayake NS, Rathnayaka-Mudiyanselage IW, Dos Santos NM, Schrader J, Koide T, Marques MV.   +8 more
europepmc   +1 more source

Helicase and Capping Enzyme Active Site Mutations in Brome Mosaic Virus Protein 1a Cause Defects in Template Recruitment, Negative-Strand RNA Synthesis, and Viral RNA Capping

, 2000
Tero Ahola, Johan A. den Boon, Paul Ahlquist   +2 more
openalex   +1 more source