RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions
Nucleic Acids Research, 2009 Retroviruses rely on host RNA-binding proteins to modulate various steps in their replication. Previously several animal retroviruses were determined to mediate Dhx9/RNA helicase A (RHA) interaction with a 5′ terminal post-transcriptional control element
Cheryl Bolinger +4 more
semanticscholar +1 more source
Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless
bioRxiv, 2022 Unwinding RNA secondary structures by RNA helicases is essential for RNA metabolism. How the basic unwinding reaction of DExH-type helicases is regulated by their accessory domains is unresolved.
P. Jagtap +7 more
semanticscholar +1 more source
The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis [PDF]
, 2019 Post-transcriptional mechanisms have the potential to influence complex changes in gene expression, yet their role in cell fate transitions remains largely unexplored.
Aigner, S. +21 more
core +3 more sources
Structural basis of Zika virus helicase in recognizing its substrates
Protein & Cell, 2016 The recent explosive outbreak of Zika virus (ZIKV) infection has been reported in South and Central America and the Caribbean. Neonatal microcephaly associated with ZIKV infection has already caused a public health emergency of international concern.
Hongliang Tian +14 more
doaj +1 more source
Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer [PDF]
, 2017 Purpose: DEAD box protein 3 (DDX3) is an RNA helicase with oncogenic properties that shuttles between the cytoplasm and nucleus. The majority of DDX3 is found in the cytoplasm, but a subset of tumors has distinct nuclear DDX3 localization of yet unknown ...
Bol, Guus M. +10 more
core +2 more sources
Dual Roles of RNA Helicase A in CREB-Dependent Transcription
Molecular and Cellular Biology, 2001 Satoko Aratani +8 more
openalex +2 more sources
Association of RNA Helicase A with Human Immunodeficiency Virus Type 1 Particles*
Journal of Biological Chemistry, 2006 RNA helicase A (RHA) belongs to the DEAH family of proteins that are capable of unwinding double-stranded RNA structure. In addition to its involvement in the metabolism of cellular RNA, RHA has been shown to stimulate RNA transcription from the long ...
B. B. Roy +6 more
semanticscholar +1 more source
Evaluation of an ASFV RNA Helicase Gene A859L for Virus Replication and Swine Virulence
Viruses, 2021 African swine fever virus (ASFV) is producing a devastating pandemic that, since 2007, has spread to a contiguous geographical area from central Europe to Asia. In July 2021, ASFV was detected in the Dominican Republic, the first report of the disease in
E. Ramírez-Medina +7 more
semanticscholar +1 more source
Repetitive RNA unwinding by RNA helicase A facilitates RNA annealing
Nucleic Acids Research, 2014 Helicases contribute to diverse biological processes including replication, transcription and translation. Recent reports suggest that unwinding of some helicases display repetitive activity, yet the functional role of the repetitiveness requires further
H. Koh, L. Xing, L. Kleiman, Sua Myong
semanticscholar +1 more source
Transcription as a Threat to Genome Integrity [PDF]
, 2016 Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and genome rearrangements, that constitute the basis for evolution.
Aguilera López, Andrés +1 more
core +1 more source