Results 251 to 260 of about 2,276,335 (391)

Leveraging RNA interference technology for selective and sustainable crop protection. [PDF]

Front Plant Sci
Qi HY, Zhang DD, Liu B, Chen JY, Han D, Wang D.   +5 more
europepmc   +1 more source

Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells

Nature Microbiology, 2016
Yang Li, Yang Li, Megha Basavappa, Jinfeng Lu, Shuwei Dong, D. Cronkite, J. T. Prior, H. Reinecker, P. Hertzog, Yanhong Han, Wan-Xiang Li, Sihem Cheloufi, Fedor V. Karginov, S. Ding, K. Jeffrey   +14 more
semanticscholar   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Gene Silencing of Olfactory Receptor Coreceptor by Systemic RNA Interference in Callosobruchus maculatus. [PDF]

J Chem Ecol
Shimomura K, Sakita K, Terajima T, Tomizawa M.   +3 more
europepmc   +1 more source

RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase [PDF]

, 2002
Olivier Donzé
openalex   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Less is more: slow-codon windows enhance eGFP mRNA resilience against RNA interference. [PDF]

J R Soc Interface
Müller JA, Schwake G, Reiser A, Woschée D, Alirezaeizanjani Z, Rädler JO, Rudorf S.   +6 more
europepmc   +1 more source

Bax Inhibitor-1 Is Overexpressed in Prostate Cancer and Its Specific Down-Regulation by RNA Interference Leads to Cell Death in Human Prostate Carcinoma Cells [PDF]

, 2003
Michal Grzmil, Paul Thelen, Bernhard Hemmerlein, Stefan Schweyer, Silke Voigt, Dina Mury, Peter Burfeind   +6 more
openalex   +1 more source

Eco‐Fabricated Nanowave‐Textured Implants Drive Microtubule‐Assisted Nuclear Mechanotransduction and Chromatin Modification: Biophysical Priming for Osteogenesis and Bone Regeneration

Advanced Functional Materials, EarlyView.
Eco‐friendly nanowave‐textured implants produced via femtosecond laser fabrication enhance bone regeneration by orchestrating a precise mechanotransduction cascade. This nanotopography directs mesenchymal stem cell alignment and cytoskeletal organization, triggering changes in nuclear shape and chromatin acetylation that prime cells for osteogenesis ...
Bosu Jeong, Ji‐Young Yoon, Junyong Ahn, Byunghak Lee, Sung‐Min Park, Jae‐Heon Kim, Buuvee Bayarkhangai, Yu Jin Kim, Sak Lee, Jonathan C. Knowles, Moon‐Young Kim, DongJun Lee, Sang‐Hoon Rhee, Hae‐Hyoung Lee, Hae‐Won Kim, Jung‐Hwan Lee   +15 more
wiley   +1 more source

Pathogenetic therapeutic approaches for endocrine diseases based on antisense oligonucleotides and RNA-interference. [PDF]

Front Endocrinol (Lausanne)
Golounina O, Minniakhmetov I, Salakhov R, Khusainova R, Zakharova E, Bychkov I, Mokrysheva N.   +6 more
europepmc   +1 more source