Results 61 to 70 of about 2,067,543 (238)
EBioMedicine, 2018 Background: Circulating miRNAs are known to play important roles in intercellular communication. However, the effects of exosomal miRNAs on cells are not fully understood.
Pinar Kanlikilicer +19 more
doaj
Symbiont-mediated RNA interference in insects
Proceedings of the Royal Society B: Biological Sciences, 2016 RNA interference (RNAi) methods for insects are often limited by problems with double-stranded (ds) RNA delivery, which restricts reverse genetics studies and the development of RNAi-based biocides. We therefore delegated to insect symbiotic bacteria the
M. Whitten +7 more
semanticscholar +1 more source
Random model for RNA interference yields scale free network [PDF]
, 2003 We introduce a random bit-string model of post-transcriptional genetic regulation based on sequence matching. The model spontaneously yields a scale free network with power law scaling with $ \gamma=-1$ and also exhibits log-periodic behaviour.
arxiv +1 more source
BPPart and BPMax: RNA-RNA Interaction Partition Function and Structure Prediction for the Base Pair Counting Model [PDF]
arXiv, 2019 RNA-RNA interaction (RRI) is ubiquitous and has complex roles in the cellular functions. In human health studies, miRNA-target and lncRNAs are among an elite class of RRIs that have been extensively studied. Bacterial ncRNA-target and RNA interference are other classes of RRIs that have received significant attention.
arxiv
In silico evidence of the relationship between miRNAs and siRNAs [PDF]
arXiv, 2007 Both short interfering RNAs (siRNAs) and microRNAs (miRNAs) mediate the repression of specific sequences of mRNA through the RNA interference pathway. In the last years several experiments have supported the hypothesis that siRNAs and miRNAs may be functionally interchangeable, at least in cultured cells.
arxiv
EBioMedicine, 2019 Background: Inflammatory mediator prostaglandin E2–prostaglandin E2 receptor EP3 (PTGER3) signaling is critical for tumor-associated angiogenesis, tumor growth, and chemoresistance. However, the mechanism underlying these effects in ovarian cancer is not
Cristian Rodriguez-Aguayo +17 more
doaj
Branched RNA: A New Architecture for RNA Interference
Journal of Nucleic Acids, 2011 Branched RNAs with two and four strands were synthesized. These structures were used to obtain branched siRNA. The branched siRNA duplexes had similar inhibitory capacity as those of unmodified siRNA duplexes, as deduced from gene silencing experiments ...
Anna Aviñó +3 more
doaj +1 more source
RNA interference is essential for cellular quiescence
Science, 2016 RNAi soothes the path to quiescence Cells, such as those in stem cell niches and immunity memory cells, can exist in a nondividing, quiescent state, from which they can be aroused with the appropriate signal.
B. Roche, B. Arcangioli, R. Martienssen
semanticscholar +1 more source
Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways
Science, 2013 RNA on the Attack Plant microbial pathogens often work through protein effectors that are delivered into the plant cells to disrupt critical cellular functions. Weiberg et al. (p.
Arne Weiberg +7 more
semanticscholar +1 more source
Small Interference RNA (siRNA) [PDF]
بیولوژی کاربردی, 2016 Infectious diseases caused by microorganisms are still major causes of death all over the world and the increasing number of their resistant strains results in great concerns.
Mohammad Abootaleb +1 more
doaj