Results 71 to 80 of about 2,067,543 (238)

RNA interference in glial cells for nerve injury treatment

Journal of Tissue Engineering, 2020
Drivers of RNA interference are potent for manipulating gene and protein levels, which enable the restoration of dysregulated mRNA expression that is commonly associated with injuries and diseases.
Junquan Lin, Seung Bin Jo, Tae-Hyun Kim, Hae-Won Kim, Sing Yian Chew   +4 more
doaj   +1 more source

Exosomes: Nanoparticulate tools for RNA interference and drug delivery

Journal of Cellular Physiology, 2017
Exosomes are naturally occurring extracellular vesicles released by most mammalian cells in all body fluids. Exosomes are known as key mediators in cell‐cell communication and facilitate the transfer of genetic and biochemical information between distant
F. Shahabipour, N. Barati, T. Johnston, G. Derosa, P. Maffioli, A. Sahebkar   +5 more
semanticscholar   +1 more source

EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans [PDF]

, 2000
Anne M. Smardon, Jill M. Spoerke, Steven C. Stacey, Marcia E. Klein, Nancy A. Mackin, Eleanor M. Maine   +5 more
openalex   +2 more sources

Engineering RNA Virus Interference via the CRISPR/Cas13 Machinery in Arabidopsis

Viruses, 2018
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems are key immune mechanisms helping prokaryotic species fend off RNA and DNA viruses.
R. Aman, Ahmed Mahas, Haroon Butt, Fatimah Aljedaani, Magdy M. Mahfouz   +4 more
semanticscholar   +1 more source

The initiation of RNA interference (RNAi) in plants.

Current opinion in plant biology, 2021
Yu-Hung Hung, R. Slotkin
semanticscholar   +1 more source

Shapes of interacting RNA complexes [PDF]

arXiv, 2014
Shapes of interacting RNA complexes are studied using a filtration via their topological genus. A shape of an RNA complex is obtained by (iteratively) collapsing stacks and eliminating hairpin loops. This shape-projection preserves the topological core of the RNA complex and for fixed topological genus there are only finitely many such shapes.Our main ...
arxiv  

The Role of RNA Interference (RNAi) in Arbovirus-Vector Interactions

Viruses, 2015
RNA interference (RNAi) was shown over 18 years ago to be a mechanism by which arbovirus replication and transmission could be controlled in arthropod vectors.
C. Blair, K. Olson
semanticscholar   +1 more source

Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference

Nucleic Acids Research, 2015
The discovery that the machinery of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 bacterial immune system can be re-purposed to easily create deletions, insertions and replacements in the mammalian genome has revolutionized ...
R. Barrangou, A. Birmingham, S. Wiemann, R. Beijersbergen, V. Hornung, A. Smith   +5 more
semanticscholar   +1 more source

Overview of RNA interference therapeutics [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2012
Since the term RNA interference (RNAi) was coined in 1998, much knowledge about RNAi has accumulated. Presently,RNAi is known as a power tool for studying gene function as well as a potential therapeutic molecular technique for a widerange of disorders ...
Nattanan T-Thienprasert Panjaworayan
doaj  

Maturation of siRNA by strand separation: Steered Molecular dynamics study [PDF]

arXiv, 2019
RNA interference, particularly siRNA induced gene silencing is becoming an important avenue of modern therapeutics. The siRNA is delivered to the cells as short double helical RNA which becomes single stranded for forming the RISC complex. Significant experimental evidence is available for most of the steps except the process of the separation of the ...
arxiv