Results 271 to 280 of about 753,590 (330)
Evolutionary origins of archaeal and eukaryotic RNA-guided RNA modification in bacterial IS110 transposons. [PDF]
Vaysset H+4 more
europepmc +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Modulation of m<sup>6</sup>A RNA modification by DAP3 in cancer cells. [PDF]
Han J+11 more
europepmc +1 more source
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki+11 more
wiley +1 more source
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti+5 more
wiley +1 more source
Comprehensive nucleoside analysis of archaeal RNA modification profiles reveals an m<sup>7</sup>G in the conserved P loop of 23S rRNA. [PDF]
Tsai YL+10 more
europepmc +1 more source
FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang+5 more
wiley +1 more source
N6-methyladenosine RNA modification promotes Severe Fever with Thrombocytopenia Syndrome Virus infection. [PDF]
Chen Z+7 more
europepmc +1 more source
Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines
Albert Weixlbaumer+6 more
openalex +2 more sources