Results 11 to 20 of about 883,773 (191)
BiosensorsMagnesium ions (Mg2+) play an important role in animal health, with their concentration in the bloodstream serving as a key indicator for hypomagnesemia diagnosis.
Hui Wang +12 more
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Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core +3 more sources
Programmable Edge-to-Edge Assembly of RNA Nanostructures. [PDF]
ACS NanoAbstract Constructing complex three-dimensional RNA nanostructures requires precise molecular connectors for controlled self-assembly. Existing RNA–RNA connectors, such as kissing loops, are restricted to coaxial, end-to-end joining, limiting the range of accessible geometries.
Geary C +4 more
europepmc +4 more sources
Molecules, 2020 Guanosine- and uridine-rich single-stranded RNA (GU-rich RNA) is an agonist of Toll-like receptor (TLR) 7 and TLR8 and induces strong immune responses. A nanostructured GU-rich RNA/DNA assembly prepared using DNA nanotechnology can be used as an adjuvant
Fusae Komura +4 more
doaj +1 more source
Axon micro-dissection and transcriptome profiling reveals the in vivo RNA content of fully differentiated myelinated motor axons [PDF]
, 2020 Axonal protein synthesis has been shown to play a role in developmental and regenerative growth, as well as in the maintenance of the axoplasm in steady state.
core +2 more sources
Profiling stress-triggered RNA condensation with photocatalytic proximity labeling
Nature Communications, 2023 Stress granules (SGs) are highly dynamic cytoplasmic membrane-less organelles that assemble when cells are challenged by stress. RNA molecules are sorted into SGs where they play important roles in maintaining the structural stability of SGs and ...
Ziqi Ren, Wei Tang, Luxin Peng, Peng Zou
doaj +1 more source
Applied Sciences, 2021 Ribozymes are catalytic RNAs that are attractive platforms for the construction of nanoscale objects with biological functions. We designed a dimeric form of the Tetrahymena group I ribozyme as a unit structure in which two ribozymes were connected in a ...
Junya Akagi +8 more
doaj +1 more source
Nanobase.org: a repository for DNA and RNA nanostructures
Nucleic Acids Research, 2021 Abstract We introduce a new online database of nucleic acid nanostructures for the field of DNA and RNA nanotechnology. The database implements an upload interface, searching and database browsing. Each deposited nanostructures includes an image of the nanostructure, design file, an optional 3D view, and additional metadata such as ...
Erik Poppleton +4 more
openaire +2 more sources
RNA-specific ribonucleotidyl transferases [PDF]
, 2007 RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W. +5 more
core +1 more source
High-throughput single-molecule quantification of individual base stacking energies in nucleic acids
Nature Communications, 2023 Base stacking interactions between adjacent bases in DNA and RNA are important for many biological processes and in biotechnology applications. Previous work has estimated stacking energies between pairs of bases, but contributions of individual bases ...
Jibin Abraham Punnoose +9 more
doaj +1 more source