Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway [PDF]
, 2012 tRNA precursors, which are transcribed by RNA polymerase III, undergo end-maturation, splicing and base modifications. Hypomodified tRNAs, such as tRNAVal(AAC), lacking 7-methylguanosine and 5-methylcytidine modifications, are subject to degradation by a
Boguta, Magdalena +3 more
core +1 more source
Nanostructure-Supported Evaporation Underneath a Growing Bubble
, 2019 High porosity nanostructured coatings have been extensively studied for their use in enhancing liquid-to-vapor phase change due to their ability to wick liquids laterally across surfaces during boiling.
Matthew McCarthy (1746856) +1 more
core +7 more sources
In vivo production of RNA nanostructures via programmed folding of single-stranded RNAs
Nature Communications, 2018 RNA nanostructures have been demonstrated in a range of biological applications, but their assembly and delivery to cells is difficult. Here the authors demonstrate the in vivo assembly of a RNA nanostructure from a single transcript inside the cellular ...
Mo Li +8 more
doaj +1 more source
Talanta Open, 2023 The complexity of procedures, concentration dependency, and time consumption associated with traditional microRNA analysis platforms render them unsuitable for point-of-care (POC) diagnostics.
Zahra Sahafnejad +5 more
doaj +1 more source
An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei [PDF]
, 2007 RNA editing in the sleeping sickness parasite Trypanosoma brucei remodels mitochondrial transcripts by the addition and deletion of uridylates as specified by guide RNAs.
Schnaufer, Achim; id_orcid +4 more
core +1 more source
RNA-Peptide Conjugation through an Efficient Covalent Bond Formation
Applied Sciences, 2020 Many methods for modification of an oligonucleotide with a peptide have been developed to apply for the therapeutic and diagnostic applications or for the assembly of nanostructure.
Shun Nakano +3 more
doaj +1 more source
RNA secondary structure prediction with pseudoknots: Contribution of algorithm versus energy model. [PDF]
PLoS ONE, 2018 RNA is a biopolymer with various applications inside the cell and in biotechnology. Structure of an RNA molecule mainly determines its function and is essential to guide nanostructure design.
Hosna Jabbari +2 more
doaj +1 more source
Composing RNA Nanostructures from a Syntax of RNA Structural Modules [PDF]
Nano Letters, 2017 Natural stable RNAs fold and assemble into complex three-dimensional architectures by relying on the hierarchical formation of intricate, recurrent networks of noncovalent tertiary interactions. These sequence-dependent networks specify RNA structural modules enabling orientational and topological control of helical struts to form larger self-folding ...
Cody Geary +4 more
openaire +3 more sources
An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]
, 2013 Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Darren M. Gowers (485354) +39 more
core +2 more sources
RNA Nanoparticles and Method of Use Thereof [PDF]
, 2020 The presently-disclosed subject matter relates to an artificial RNA nanostructure and method of use thereof. In particular, the presently-disclosed subject matter relates to RNA nanoparticles and RNA dendrimers, and methods of disease diagnosis and ...
Li, Hui, Luo, Wei, Guo, Peixuan
core +1 more source