Results 21 to 30 of about 708,746 (292)
Single-molecule observations of RNA–RNA kissing interactions in a DNA nanostructure
Biomaterials Science, 2016 Unique complex formation of RNA molecules through specific hairpin loop interaction was visualized in a DNA origami.
Guillaume Durand +2 more
exaly +4 more sources
A polyphenol-assisted IL-10 mRNA delivery system for ulcerative colitis
Acta Pharmaceutica Sinica B, 2022 With the development of synthesis technology, modified messenger RNA (mRNA) has emerged as a novel category of therapeutic agents for a broad of diseases.
Zhejie Chen +8 more
doaj +1 more source
Molecules, 2023 The multimolecular assembly of three-dimensionally structured proteins forms their quaternary structures, some of which have high geometric symmetry. The size and complexity of protein quaternary structures often increase in a hierarchical manner, with ...
Mst. Ayesha Siddika +6 more
doaj +1 more source
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core +3 more sources
Catalytic RNA Oligomers Formed by Co-Oligomerization of a Pair of Bimolecular RNase P Ribozymes
Molecules, 2022 Naturally occurring ribozymes with a modular architecture are promising platforms for construction of RNA nanostructures because modular redesign enables their oligomerization.
Mst. Ayesha Siddika +7 more
doaj +1 more source
Axon micro-dissection and transcriptome profiling reveals the in vivo RNA content of fully differentiated myelinated motor axons [PDF]
, 2020 Axonal protein synthesis has been shown to play a role in developmental and regenerative growth, as well as in the maintenance of the axoplasm in steady state.
Sotelo-Silveira, José Roberto +3 more
core +3 more sources
Molecules, 2020 Guanosine- and uridine-rich single-stranded RNA (GU-rich RNA) is an agonist of Toll-like receptor (TLR) 7 and TLR8 and induces strong immune responses. A nanostructured GU-rich RNA/DNA assembly prepared using DNA nanotechnology can be used as an adjuvant
Fusae Komura +4 more
doaj +1 more source
Profiling stress-triggered RNA condensation with photocatalytic proximity labeling
Nature Communications, 2023 Stress granules (SGs) are highly dynamic cytoplasmic membrane-less organelles that assemble when cells are challenged by stress. RNA molecules are sorted into SGs where they play important roles in maintaining the structural stability of SGs and ...
Ziqi Ren, Wei Tang, Luxin Peng, Peng Zou
doaj +1 more source
Applied Sciences, 2021 Ribozymes are catalytic RNAs that are attractive platforms for the construction of nanoscale objects with biological functions. We designed a dimeric form of the Tetrahymena group I ribozyme as a unit structure in which two ribozymes were connected in a ...
Junya Akagi +8 more
doaj +1 more source
Nanobase.org: a repository for DNA and RNA nanostructures
Nucleic Acids Research, 2021 Abstract We introduce a new online database of nucleic acid nanostructures for the field of DNA and RNA nanotechnology. The database implements an upload interface, searching and database browsing. Each deposited nanostructures includes an image of the nanostructure, design file, an optional 3D view, and additional metadata such as ...
Erik Poppleton +4 more
openaire +2 more sources