Results 71 to 80 of about 883,773 (191)

Inducing macrophage M2-Type polarization via anodized anisotropic TiO2 nanoporous topography on titanium surfaces

BMC Oral Health
Background Dental implant success critically depends on soft tissue integration (STI) to prevent peri-implantitis. Macrophages, key immune regulators, exhibit distinct pro-inflammatory (M1) or anti-inflammatory/pro-healing (M2) phenotypes, significantly ...
Siyu Xie, Wei Wei, Bin Luo, Jiangqi Hu, Yunping Lu, Lin He, Xiaoyu Wang, Xu Sun, Qingsong Jiang, Tianxiao Han   +9 more
doaj   +1 more source

Intein-mediated site-specific conjugation of Quantum Dots to proteins in vivo

Journal of Nanobiotechnology, 2009
We describe an intein based method to site-specifically conjugate Quantum Dots (QDs) to target proteins in vivo. This approach allows the covalent conjugation of any nanostructure and/or nanodevice to any protein and thus the targeting of such material ...
Skourides Paris A, Andreou Maria, Charalambous Anna   +2 more
doaj   +1 more source

Base-specific spin-labeling of RNA for structure determination [PDF]

, 2007
To facilitate the measurement of intramolecular distances in solvated RNA systems, a combination of spin-labeling, electron paramagnetic resonance (EPR), and molecular dynamics (MD) simulation is presented. The fairly rigid spin label 2,2,5,5-tetramethyl-
Olav Schiemann, Mu, Yuguang, Prisner, Thomas F., Stock, G., Engels, J.W., Prisner, TF., Thomas F. Prisner, Engels, Joachim W. (Prof. Dr.), Stock, Gerhard, Piton, N., Schiemann, Olav, Gerhard Stock, Nelly Piton, Piton, Nelly, Mu, Y., Yuguang Mu, Joachim W. Engels   +16 more
core   +1 more source

Introduction, synthesis procedures, and applications of organic-inorganic hybrid nanoflowers in biosciences

مجله دانشگاه علوم پزشکی بیرجند, 2023
Organic-inorganic hybrid nanoflowers with flower-like morphology are new nanostructures comprising organic and inorganic components. In general, the organic component of hybrid nanoflowers mostly consists of proteins, DNA, RNA, plant extracts ...
Khashayar Vojdanitalab, Mina Saeedi, Mohammad Ali Faramarzi, Somayeh Mojtabavi   +3 more
doaj  

Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry

, 2012
The VapBC toxin-antitoxin (TA) family is the largest of nine identified TA families. The toxin, VapC, is a metal-dependent ribonuclease that is inhibited by its cognate antitoxin, VapB. Although the VapBCs are the largest TA family, little is known about
Cook, Gregory M., Mackay, Joel, Cursons, Raymond T., Duyvestyn, Johanna Maria, Mckenzie, Joanna L., Smith, Tony C., Bendak, Katerina, Smith, Tony, Cursons, R. A.Y., Mackay, Joel P., Arcus, Vickery L., Duyvestyn, Johanna M., McKenzie, Joanna Leigh, https://orcid.org/   +13 more
core   +1 more source

RNA Movies 2: sequential animation of RNA secondary structures [PDF]

, 2007
Kaiser A, Krüger J, Evers DJ. RNA Movies 2: sequential animation of RNA secondary structures. NUCLEIC ACIDS RESEARCH.
Krüger, Jan, Evers, Dirk J., Kaiser, Alexander   +2 more
core   +1 more source

Amplification-free CRISPR/Cas13a-based electrochemical biosensor for the detection of circulating tumor RNA using RNA-3Ag⁺ probes on Au porous-lattice nanoelectrode

Journal of Biological Engineering
Circulating tumor RNA (ctRNA) is a sensitive biomarker for early cancer diagnosis, offering real-time gene expression profiles and tumor-specific signatures missed by circulating tumor DNA.
Yu-Rim Lee, Myeong-Jun Lee, Sang-Nam Lee, Jeong-Woo Choi   +3 more
doaj   +1 more source

Aptamer-based nanoparticle drug delivery system designed for targeting GPC3-positive liver cancer

Journal of Pharmaceutical Analysis
Nucleic acid aptamers, short single-stranded DNA (ssDNA) or RNA molecules generated via systematic evolution of ligands by exponential enrichment (SELEX), have emerged as promising alternatives to traditional antibodies owing to their exceptional ...
Hongxin Zhou, Shuangshuang Dong, Zhan Si, Hao Niu, Jianwen Mao, Yiran Chen, Yuhuan Li, Weizhong Wu   +7 more
doaj   +1 more source

Development of a Dual Gene-Targeted Multi-Sirna with Branched Structure and Its Role in the Therapy of Liver Cancer

Pharmaceuticals
Background: Hepatocellular carcinoma (HCC) remains a major global health challenge with limited therapeutic options. Although RNA interference (RNAi) enables precise gene silencing, its clinical application is restricted by siRNA instability, inefficient
Mingdong Lu, Wenqin Jiang, Zhekai Liu, Yiqing Liu, Fangli Wu, Weibo Jin   +5 more
doaj   +1 more source

Electrically Guided DNA Immobilization and Multiplexed DNA Detection with Nanoporous Gold Electrodes

Nanomaterials, 2018
Molecular diagnostics have significantly advanced the early detection of diseases, where the electrochemical sensing of biomarkers (e.g., DNA, RNA, proteins) using multiple electrode arrays (MEAs) has shown considerable promise.
Jovana Veselinovic, Zidong Li, Pallavi Daggumati, Erkin Seker   +3 more
doaj   +1 more source