Results 81 to 90 of about 883,773 (191)

Mesoscopic Structure of Lipid Nanoparticles Studied by Small-Angle X-Ray Scattering: A Spherical Core-Triple Shell Model Analysis

open access: yesMembranes
Lipid nanoparticles (LNPs) are widely recognized as effective drug delivery systems for RNA therapeutics because their efficacy is critically dependent on structural organization.
Hao Li   +7 more
doaj   +1 more source

Biomimetic mineralization‐inspired formulation‐adjuvant integrated circRNA nanovaccine against COVID‐19

open access: yesInterdisciplinary Medicine
Conventional RNA‐based vaccines rely on lipid nanoparticles (LNPs) for delivery; however, concerns exist regarding the potential systemic toxicity of their chemical composition, and their immune‐activating capabilities require further enhancement ...
Liangru Lin   +10 more
doaj   +1 more source

DNA Nanocarriers for Delivery of sgRNA/Cas9 Ribonucleoprotein

open access: yesNano Biomedicine and Engineering
DNA has been widely employed as a building block for the construction of sophisticated nanostructures with pre-designed sizes and shapes by complementary base pairing.
Hanyin Zhu   +4 more
doaj   +1 more source

Cytoplasmic RNA-dependent RNA-synthesis in maturing chicken erythrocytes. [PDF]

open access: yes, 1976
Includes bibliographical references.An RNA-dependent RNA polymerase from ribosomes of maturing chicken erythrocytes was investigated. Concurrent with an increase in globin and RNA synthesis during phenylhydrazine induced anaemia, the total and specific ...
Boyd, Malcolm Charles David
core   +1 more source

RNA nanostructures for targeted drug delivery and imaging

open access: yesRNA Biology
The RNA molecule plays a pivotal role in many biological processes by relaying genetic information, regulating gene expression, and serving as molecular machines and catalyzers. This inherent versatility of RNA has fueled significant advancements in the field of RNA nanotechnology, driving the engineering of complex nanoscale architectures toward ...
Laura Teodori   +2 more
openaire   +3 more sources

Long-term monitoring of ultratrace nucleic acids using tetrahedral nanostructure-based NgAgo on wearable microneedles

open access: yesNature Communications
Real-time and continuous monitoring of nucleic acid biomarkers with wearable devices holds potential for personal health management, especially in the context of pandemic surveillance or intensive care unit disease.
Bin Yang   +3 more
doaj   +1 more source

Functions of RNAi Pathways in Ribosomal RNA Regulation

open access: yes
Argonaute proteins, guided by small RNAs, play crucial roles in gene regulation and genome protection through RNA interference (RNAi)-related mechanisms.
Shatskikh, Aleksei S   +2 more
core   +1 more source

Review of Fiber-Optic Localized Surface Plasmon Resonance Sensors: Geometries, Fabrication Technologies, and Bio-Applications

open access: yesPhotonic Sensors
Localized surface plasmon resonance (LSPR) biosensors, which enable nanoscale confinement and manipulation of light, offer the enhanced sensitivity and electromagnetic energy localization.
Mengdi Lu   +5 more
doaj   +1 more source

Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells

open access: yesInternational Journal of Nanomedicine, 2016
Rosa Di Liddo,1,2 Paola Aguiari,3 Silvia Barbon,1,2 Thomas Bertalot,1 Amit Mandoli,1 Alessia Tasso,1 Sandra Schrenk,1 Laura Iop,3 Alessandro Gandaglia,3 Pier Paolo Parnigotto,2 Maria Teresa Conconi,1,2 Gino Gerosa31Department of Pharmaceutical and ...
Di Liddo R   +11 more
doaj  

Amplification-Free Electrochemiluminescent Biosensor for Ultrasensitive Detection of Fusobacterium nucleatum Using Tetrahedral DNA-Based CRISPR/Cas12a

open access: yesCyborg and Bionic Systems
Fusobacterium nucleatum, a bacterium linked to colorectal cancer, possesses a specific gene called fadA that serves as an early diagnostic biomarker.
Xindan Zhang   +6 more
doaj   +1 more source

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