Results 141 to 150 of about 5,405 (175)

Cardiomyocyte β-arrestins mediate inflammation and cGAS-STING activation in CVB3 viral myocarditis. [PDF]

Am J Physiol Heart Circ Physiol
Lucero EY, Jiang H, D'Anniballe V, Pakharukova N, Galtes D, Bassford D, Jyothidasan A, Knowlton KU, Gunn MD, Lefkowitz RJ, Rockman HA.   +10 more
europepmc   +1 more source

Unintegrated HIV-1 DNA recruits cGAS via its histone-binding domain to escape innate immunity. [PDF]

Proc Natl Acad Sci U S A
Jahan C, Bonnet-Madin L, Machida S, Sobhian B, Thenin-Houssier S, Benkirane M.   +5 more
europepmc   +1 more source

Profiling Nucleotide Signalling Pathways and STING Agonist Activity with a Nucleotide Library

Bekere I, Öllinger R, Schrimpf MR, Rad R, de Oliveira Mann CC.   +4 more
europepmc   +1 more source

Phylogeny and Evolution of RNA 3′-Nucleotidyltransferases in Bacteria

Journal of Molecular Evolution, 2019
The tRNA nucleotidyltransferases and poly(A) polymerases belong to a superfamily of nucleotidyltransferases. The amino acid sequences of a number of bacterial tRNA nucleotidyltransferases and poly(A) polymerases have been used to construct a rooted, neighbor-joining phylogenetic tree.
George H Jones
openaire   +4 more sources

The polynucleotide ligase and RNA capping enzyme superfamily of covalent nucleotidyltransferases

Current Opinion in Structural Biology, 2004
ATP- and NAD(+)-dependent DNA ligases, ATP-dependent RNA ligases and GTP-dependent mRNA capping enzymes comprise a superfamily of proteins that catalyze nucleotidyl transfer to polynucleotide 5' ends via covalent enzyme-(lysyl-N)-NMP intermediates. The superfamily is defined by five peptide motifs that line the nucleotide-binding pocket and contribute ...
Stewart, Shuman, Christopher D, Lima
openaire   +4 more sources

Transfer RNA nucleotidyltransferase repairs all transfer RNAs randomly

Journal of Molecular Biology, 1977
Total Escherichia coli transfer RNA was converted to tRNA-C-C by periodate oxidation and partially repaired with either E. coli or rabbit liver tRNA nucleotidyltransferase. Aminoacylation of the partially repaired molecules indicated that individual tRNA species were each repaired to the same extent as the total population of molecules.
M P, Deutscher, J A, Evans
openaire   +2 more sources

Purification of transfer-RNA-nucleotidyltransferase from E. Coli B

Biochemical and Biophysical Research Communications, 1970
Abstract Transfer-RNA-nucleotidyltransferase has been purified 1400-fold from E. coli B by liquid polymer phase fractionation and chromatography on DEAE-cellulose, hydroxylapatite, and QAE-Sephadex. The final preparation contains no detectable RNase I, RNase II, polynucleotide phosphorylase, ATPase, CTPase, or any of the aminoacyl-tRNA ...
J P, Miller, G R, Philipps
openaire   +2 more sources

t-RNA-nucleotidyltransferase activity in Lupinus luteus seeds

Phytochemistry, 1975
Abstract t -RNA-nucleotidyltransferase activity was detected in Lupinus luteus seed.The enzyme was partly purified, and some of its properties are described.
Henryk Cudny, Maciej Pietrzak, Slawomir Bartkowiak   +2 more
openaire   +1 more source

Transfer RNA metabolism in Escherichia coli cells deficient in tRNA nucleotidyltransferase

Journal of Molecular Biology, 1977
We have investigated the role of tRNA nucleotidyltransferase in transfer RNA metabolism using mutants ( cca mutants) of Escherichia coli deficient in this enzyme. Extracts of the most defective strain contained cca mutation into a variety of genetic backgrounds. However, tRNA from stationary phase cells was somewhat more defective.
M P, Deutscher, J J, Lin, J A, Evans
openaire   +2 more sources

Apparent non-involvement of transfer RNA nucleotidyltransferase in the biosynthesis of Escherichia coli suppressor transfer RNAs

Journal of Molecular Biology, 1975
Abstract Transfer RNA nucleotidyltransferase has previously been shown to be required for the normal growth of Escherichia coli and for the biosynthesis of some bacteriophage T4 tRNAs. In order to obtain information about the involvement of this enzyme in E.
J W, Morse, M P, Deutscher
openaire   +2 more sources