Results 211 to 220 of about 2,760,256 (386)

The RNA polymerase II core subunit 11 interacts with keratin 19, a component of the intermediate filament proteins [PDF]

, 1999
Tiziana Bruno, Nicoletta Corbi, Monica Di Padova, Roberta De Angelis, Aristide Floridi, Claudio Passananti, Maurizio Fanciulli   +6 more
openalex   +1 more source

RNA polymerase II clustering through carboxy-terminal domain phase separation

Nature Structural & Molecular Biology, 2018
M. Boehning, C. Dugast-Darzacq, M. Rankovic, A. Hansen, Taekyung Yu, H. Marie-Nelly, D. McSwiggen, G. Kokic, G. Dailey, P. Cramer, X. Darzacq, M. Zweckstetter   +11 more
semanticscholar   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

RNA polymerase II is a polar roadblock to a progressing DNA fork. [PDF]

Nat Commun
Kay TM, Inman JT, Lubkowska L, Le TT, Qian J, Hall PM, Batra S, Remus D, Wang D, Kashlev M, Wang MD.   +10 more
europepmc   +1 more source

Crystal structure of the C17/25 subcomplex from Schizosaccharomyces pombe RNA polymerase III [PDF]

, 2011
Haruhiko Ehara, Shun‐ichi Sekine, Shigeyuki Yokoyama   +2 more
openalex   +1 more source

Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II

Nature, 2018
Huasong Lu, Dan Yu, A. Hansen, S. Ganguly, Rongdiao Liu, A. Heckert, X. Darzacq, Qiang Zhou   +7 more
semanticscholar   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Discovery of a Novel Non-Nucleoside Inhibitor of RNA-Dependent RNA Polymerase Against Dengue Virus. [PDF]

MedComm (2020)
He XM, Zou LF, Yu JT, Yang TJ, Lu ZB, Cao HH, Li W, Chen B, Zhao W, Zuo JP, Yu LZ, Liu JS.   +11 more
europepmc   +1 more source

Analyses of a whole-genome inter-clade recombination map of hepatitis delta virus suggest a host polymerase-driven and viral RNA structure-promoted template-switching mechanism for viral RNA recombination

, 2017
Mei Chao, Tzu-Chi Wang, Chia-Chi Lin, Robert Wang, Wenbin Lin, Shang-En Lee, Ying-Yu Cheng, Chau‐Ting Yeh, Shan-Bei Iang   +8 more
openalex   +2 more sources

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source