Results 241 to 250 of about 991,885 (339)

Automated Label‐Free Assay for Viral Detection and Inhibitor Screening via Biomembrane‐Functionalized Microelectrode Arrays

Advanced Materials, EarlyView.
A bioelectronic sensor integrating 2D cell membranes with organic microelectrode arrays enables detection of SARS‐CoV‐2 fusion pathways. Natively‐expressed viral receptors promote monitoring of viral entry and screening of antibody‐based inhibitors.
Zixuan Lu, Jeremy Treiber, Konstantinos Kallitsis, Ekaterina Selivanovitch, Alexandra Wheeler, Maria Lopez‐Cavestany, Zhongmou Chao, Sarah L Barron, Ju An Park, Darius Hoven, Anna Scheeder, Aimee Withers, Becky M. Hess, Clemens F. Kaminski, Alberto Salleo, Anna‐Maria Pappa, Susan Daniel, Róisín M Owens   +17 more
wiley   +1 more source

Interactions Between Active Matters and Endogenous Fields

Advanced Materials, EarlyView.
This review synthesizes endogenous field information and computational methods in contexts such as cancer, wounds, and biofilms. It organizes NAMs and AAMs by sensing, transmitting, and executing functions, compares their limitations, and from these contrasts proposes design strategies for next‐generation AAMs, offering perspectives to foster ...
Jinwei Lin, Qiaoxin Guan, Jiangqi Feng, Shuqin Chen, Leilei Xu, Jianguo Guan, Samuel Sánchez   +6 more
wiley   +1 more source

Multi-omics and biochemical reconstitution reveal CDK7-dependent mechanisms controlling RNA polymerase II function at gene 5'- and 3' ends. [PDF]

Cell Rep
Luyties O, Sanford L, Rodino J, Nagel M, Jones T, Rimel JK, Ebmeier CC, Palacio M, Shelby GS, Cozzolino K, Brennan F, Hartzog A, Saucedo MB, Watts LP, Spencer S, Kugel JF, Dowell RD, Taatjes DJ.   +17 more
europepmc   +1 more source

MUTE‐Seq: An Ultrasensitive Method for Detecting Low‐Frequency Mutations in cfDNA With Engineered Advanced‐Fidelity FnCas9

Advanced Materials, EarlyView.
An advanced‐fidelity CRISPR nuclease, FnCas9‐AF2, is rationally engineered to discriminate single‐base mismatches with unprecedented level precision. Integrated into the MUTE‐Seq workflow, FnCas9‐AF2 depletes wild‐type cell‐free DNA, thereby exposing rare tumor‐derived mutant DNA (a molecular “needle in a haystack”).
Sunghyeok Ye, Jin‐Soo Kim, Myungshin Kim, Ki‐Yeon Kim, Yoon‐Ho Won, Taegun Park, Sungjae An, Haerin Jeong, Hee‐Joon Chung, In Seon Lee, Myoung‐Hee Kang, Chan Young Kang, Mi Young Kim, Jae Ho Chung, Jeong‐An Gim, Woochang Hwang, Yonggoo Kim, Song Cheol Kim, Sungho Lee, Junho K Hur, Junseok W Hur   +20 more
wiley   +1 more source

Functional genomic profiling of O-GlcNAc reveals its context-specific interplay with RNA polymerase II. [PDF]

Genome Biol
Rucli S, Descostes N, Ermakova Y, Chitnavis U, Couturier J, Boskovic A, Boulard M.   +6 more
europepmc   +1 more source

Probiotic‐Based Materials as Living Therapeutics

Advanced Materials, EarlyView.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio, Graham J. Day, Manuel Salmeron‐Sanchez   +2 more
wiley   +1 more source

Dynamic O-GlcNAcylation and phosphorylation attract and expel proteins from RNA polymerase II to regulate mRNA maturation. [PDF]

J Biomed Sci
Gondane A, Itkonen HM.
europepmc   +1 more source

The First Review on Nano‐Agricultural Applications of MXene and MBene‐Based Materials for Plant‐Immunoengineering, Controlled Protection, and Inducing Biostimulation Mechanisms

Advanced Materials, EarlyView.
MXene and MBene nanomaterials show significant potential in addressing critical challenges in biomedicine, applied biology, agriculture, and the environment. From a nano‐agricultural perspective, this relatively young field has witnessed emerging advances towards applications for plant‐immunoengineering, biostimulation, and controlled delivery ...
Alireza Rafieerad, Ahmad Amiri, Maik Böhmer, Soofia Khanahmadi   +3 more
wiley   +1 more source

Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters. [PDF]

Nat Commun
Shah SZ, Perry TN, Graziadei A, Cecatiello V, Kaliyappan T, Misiaszek AD, Müller CW, Ramsay EP, Vannini A.   +8 more
europepmc   +1 more source

Utilization of primers and primer-templates by wheat germ RNA polymerase II.

, 1982
Lynwood R. Yarbrough
openalex   +1 more source