Results 221 to 230 of about 324,915 (330)

211 MOLECULAR DETECTION OF A PRECURSOR STAGE OF OSTEOARTHRITÍS IN RNA FROM CARTILAGE OF YOUNG ADULTS WITH HIP PAIN

, 2011
Sanshiro Hashimoto, Linda J. Sandell, John C. Clohisy   +2 more
openalex   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Transport of proteins into mitochondria [PDF]

, 1985
Kroon, A. M., Neupert, Walter, Palmieri, F., Pfaller, Rupert, Pfanner, Nikolaus, Quagliariello, Ernesto, Saccone, C., Schleyer, Manfred, Schmidt, Bernd, Slater, E. C.   +9 more
core  

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

The 3'-5' exoribonuclease ISG20L2 contributes to 3' terminus maturation of 18S and 28S ribosomal RNAs. [PDF]

Nucleic Acids Res
Aubert M, Zuber H, Mommert-Tripon M, Page SL, Montel-Lehry N, Soldan V, Bosch S, Gagliardi D, Gleizes PE, O'Donohue MF.   +9 more
europepmc   +1 more source

Structural Analysis using SHALiPE to Reveal RNA G‐Quadruplex Formation in Human Precursor MicroRNA [PDF]

, 2016
Chun Kit Kwok, Aleksandr B. Sahakyan, Shankar Balasubramanian   +2 more
openalex   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

NAD⁺ restores proteostasis through splicing-dependent autophagy. [PDF]

Autophagy
Ai R, Fang EF.
europepmc   +1 more source

A comparative roadmap of PIWI-interacting RNAs across seven species reveals insights into de novo piRNA-precursor formation in mammals

Παρθένα Κωνσταντινίδου, Zuzana Loubalová, Franziska Ahrend, Aleksandr Friman, Miguel Vasconcelos Almeida, Axel Poulet, Filip Horvat, Yuejun Wang, Wolfgang Losert, Hernán Lorenzi, Petr Svoboda, Eric A. Miska, Josien C. van Wolfswinkel, Astrid D. Haase   +13 more
openalex   +1 more source

T7 Early RNAs and Escherichia coli Ribosomal RNAs are Cut from Large Precursor RNAs In Vivo by Ribonuclease III

, 1973
John J. Dunn, F. William Studier
openalex   +2 more sources