Results 221 to 230 of about 2,192,206 (343)

Advances in Functional Genomics and Biotechnology for Enhancing Therapeutic Potential of Medicinal Plants. [PDF]

Int J Mol Sci
Zaman W, Park S.
europepmc   +1 more source

Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila.

RNA: A publication of the RNA Society, 2010
K. Miyoshi, T. Miyoshi, J. Hartig, H. Siomi, M. Siomi   +4 more
semanticscholar   +1 more source

Epigenetic Silencing of RFX7 Defines a Transcriptional Axis Linking Lactate Metabolism to Immune Checkpoint Therapy in Glioblastoma

Advanced Science, EarlyView.
Glioblastoma (GBM) exhibits RFX7 silencing via promoter hypermethylation, which downregulates PIK3IP1 to activate PI3K/AKT signaling, increase lactate accumulation, and enhance histone H4K12 lactylation. This lactylation upregulates PD‐L1/CSF1 expression and drives the immunosuppressive microenvironment formation.
Liying Han, Jinpeng Zhou, Gang Zhu, Fan Chen, Leiyang Li, Wenxing Cui, Fang Sun, Tian Feng, Yue Zhang, Qiang Wang, Shuoyao Ma, Chengxuan Guo, Ziwen Zhang, Kai Wang, Jiahui Wang, Liangbo Wang, Wencong Li, Chenyi Yuan, Haixiao Liu, Liang Wang, Yan Qu   +20 more
wiley   +1 more source

Pla2g6 Deficiency Induces Neuronal Precursor Apoptosis During Neurodevelopment. [PDF]

Int J Mol Sci
Shen YJ, Liu HF, Hsu TC, Chen YC, Cheng YC.   +4 more
europepmc   +1 more source

Transfer RNA precursors are accumulated in Escherichia coli in the absence of RNase E.

European Journal of Biochemistry, 1981
B. Ray, D. Apirion
semanticscholar   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

Advanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi, Xiaoyu Han, Yanhui Lu, Yuan Chai, Baiyan Xiao, Shuo Liu, Boon Chin Heng, Tingting Wu, Tingjun Li, Qiaomei Ren, Ting Song, Le Chen, Dong Han, Yaru Guo, Xuliang Deng, Xuehui Zhang   +15 more
wiley   +1 more source

Enhanced microRNA accumulation and gene silencing efficiency through optimized precursor base pairing. [PDF]

Plant J
Llorens-Gámez JJ, García-Cano PJ, Rico-Rodrigo S, Duyos-Casanova L, Toledano-Franco S, Carbonell A.   +5 more
europepmc   +1 more source

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

Advanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang, Dongzhi Wang, Yafei Guo, Qi Zheng, Min Zhang, James Simmonds, Jian Hou, Xuemei Liu, Xuelei Lin, Xiaomin Bie, Xiansheng Zhang, Xiaohui Li, Yuan Chen, Xueyong Zhang, Cristobal Uauy, Fei Lu, Chengcai Chu, Zhixi Tian, Jun Xiao   +18 more
wiley   +1 more source

Transcriptome sequencing reveals the regulatory mechanisms during the development of small white follicles to small yellow follicles in laying hens. [PDF]

Poult Sci
Ma Y, Zhou S, Mi Y, Zhang C.
europepmc   +1 more source

Could poly(A) align the splicing sites of messenger RNA precursors?

Proceedings of the National Academy of Sciences of the United States of America, 1980
M. Bina, R. Feldmann, R. Deeley
semanticscholar   +1 more source