Results 261 to 270 of about 1,148,349 (307)
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Characterization of the ribosomal RNA precursor in Ilyanassa
Experimental Cell Research, 1972Abstract Ilyanassa embryos synthesized a high molecular weight, rapidly-labeled RNA species that, as time progressed, diminished in proportion to increasing amounts of nascent ribosomal RNA. We tentatively identify this rapidly-labeled RNA species as the ribosomal RNA precursor.
R B, Koser, J R, Collier
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Photochemistry of RNA, RNA Monomers, and Plausible Prebiotic Precursors
2023Book ...
Sean J. Hoehn +2 more
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Multiple conformations of ribosomal precursor RNA
Nature, 1975WE wish to propose an explanation for the heterogeneity shown1 by ribosomal precursor RNAs on gel electrophoresis. The clearest demonstration of this phenomenon is shown in Fig. 1. 32P-labelled RNA was eluted from single gel slices taken across the peak, and rerun in the presence of 3H-labelled marker.
J M, Slack, M L, Sartirana, U E, Loening
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Speculation on the RNA Precursor Problem
Journal of Theoretical Biology, 1997While no convincing prebiotic synthesis of RNA building blocks has been demonstrated, at least two synthetic analogues of nucleic acids have been described whose properties are remarkably similar to those of RNA. The RNA backbone is thus not the only possible solution to the problem of replicating the information stored in a sequence of purines and ...
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A precursor of globin messenger RNA
Journal of Molecular Biology, 1976Abstract The size of pulse-labeled globin messenger RNA nucleotide sequences was investigated, to determine whether newly transcribed globin mRNA molecules are larger than steady-state globin mRNA. Molecular hybridization techniques were used to compare directly the sedimentation of steady-state (unlabeled) and pulse-labeled (radioactive) globin mRNA
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Enzymatic N-riboside scission in RNA and RNA precursors
Current Opinion in Chemical Biology, 1997N-ribohydrolases and transferases act on nucleosides, nucleotides and oligonucleotides to effect base removal. Advances in mechanistic and structural analysis have established that enzymes of N-riboside scission act by combinations of leaving-group and ribosyl activation.
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Splicing of messenger RNA precursors
BioEssays, 1985AbstractThe splicing of pre‐mRNAs in vitro is accomplished by formation of RNA intermediates in a lariat form. Lariat RNAs have been recently identified in vivo supporting the validity of the proposed pathway for processing pre‐mRNAs in vitro.We have recently reported20 a partial purification scheme for a pre‐mRNA splicing activity. Purification of the
Satish Patwardhan +3 more
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A precursor for a small stable RNA (10Sa RNA) ofEscherichia coli
Molecular and General Genetics MGG, 1989Strains carrying plasmids that code for 10Sa RNA synthesize a larger molecule when the RNA processing enzyme RNase E is inactivated. The T1 fingerprint of 10Sa RNA and the larger molecule is very similar, but the latter contains additional oligonucleotides. We show that the larger RNA is converted to the smaller, mature RNA.
M N, Subbarao, D, Apirion
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Lariat RNA's as Intermediates and Products in the Splicing of Messenger RNA precursors
Science, 1984The splicing of messenger RNA precursors in vitro proceeds through an intermediate that has the 5′ end of the intervening sequence joined to a site near the 3′ splice site. This lariat structure, which has been characterized for an adenovirus 2 major late transcript, has a branch point, with 2′-5′ and 3′-5′ phosphodiester bonds emanating from a single ...
R A, Padgett +4 more
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RNA Required for Import of Precursor Proteins into Mitochondria
Science, 1984A cytoplasmic RNA moiety is necessary for posttranslational uptake of nuclear-encoded mammalian proteins destined for the mitochondrial matrix. Post-translational addition of ribonuclease to a reticulocyte lysate-programmed cell-free translation mixture inhibited subsequent import of six different mitochondrial matrix enzyme precursors into rat liver ...
F A, Firgaira +4 more
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