Results 271 to 280 of about 2,192,206 (343)

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

Lineage tracing reveals photoreceptor precursor cell subpopulations that contribute to murine retinogenesis. [PDF]

Front Cell Dev Biol
Yano JJ, Wei Z, Gajjar KJ, Barati-Stec KT, Yang E, Uyhazi KE.   +5 more
europepmc   +1 more source

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

Advanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che, Donghong Li, Huan Zhang, Tingting Xu, Juhan Li, Xuanzhou Chen, Louis D. Zhang, Shuguang Wang, Dianwen Song, Dongyong Sha   +9 more
wiley   +1 more source

T cell development from expanded hematopoietic progenitors reveals initiation control by <i>Lmo2</i> and Flt3L priming. [PDF]

Sci Immunol
Shin B, Chang SJ, MacNabb BW, Sidwell T, Williams BA, Rothenberg EV.   +5 more
europepmc   +1 more source

The <i>NFIA::CBFA2T3</i> identifies a molecularly defined subgroup of acute erythroid leukemia/erythroid sarcoma. [PDF]

Front Oncol
Brunetti M, Andersen K, Tjønnfjord GE, Zeller B, Spetalen S, Munthe-Kaas MC, Osnes LTN, Os TT, Micci F.   +8 more
europepmc   +1 more source

NAD⁺ metabolism at the host-virus interface. [PDF]

J Gen Virol
Jhandai P, Vaddadi K, Liu L.
europepmc   +1 more source

Whence the demise and fall of the RNA World?

Medvegy A, Abramov O, Kremer B, Mojzsis S.   +3 more
europepmc   +1 more source

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SPLICING OF MESSENGER RNA PRECURSORS

Annual Review of Biochemistry, 1986
Richard A Padgett, Paula J Grabowski, Maria M Konarska   +2 more
exaly   +5 more sources

Ribosomal RNA precursors in plants

Journal of Molecular Biology, 1970
Abstract A high molecular weight, rapidly-labelled ribosomal RNA precursor in the pearoot tip and in artichoke-tuber tissue is described. It has a molecular weight, determined by polyacrylamide-gel electrophoresis, of about 2.3 × 10 6 daltons. The pea precursor RNA consists of two components which can just be distinguished by gel electrophoresis ...
M E, Rogers, U E, Loening, R S, Fraser
openaire   +3 more sources