Results 51 to 60 of about 310,443 (357)
Secondary structure RNA elements control the cleavage activity of DICER
Nature Communications, 2022 MicroRNA precursors are cleaved by DICER to generate mature microRNAs in the cytoplasm. Here the authors employ high-throughput analysis of DICER cleavage activity and identify RNA secondary elements in precursor miRNAs and shRNAs, including a single ...
Trung Duc Nguyen +3 more
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Revista Brasileira de Cancerologia, 2023 1. Câncer arises gradually, preceded by histological, histochemical and cariometric (tetraploidism) or hyperdiploidism pictures which may be called morphological precursors of câncer. 2.
Aurélio Monteiro
doaj +1 more source
Polyadenylation of stable RNA precursors in vivo [PDF]
Proceedings of the National Academy of Sciences, 1998 Polyadenylation at the 3′ terminus has long been considered a specific feature of mRNA and a few other unstable RNA species. Here we show that stable RNAs in Escherichia coli can be polyadenylated as well. RNA molecules with poly(A) tails are the major products that accumulate for essentially all stable RNA ...
Zhongwei Li +2 more
openaire +3 more sources
Assessing the Gene Content of the Megagenome: Sugar Pine (Pinus lambertiana). [PDF]
, 2016 Sugar pine (Pinus lambertiana Douglas) is within the subgenus Strobus with an estimated genome size of 31 Gbp. Transcriptomic resources are of particular interest in conifers due to the challenges presented in their megagenomes for gene identification ...
Delfino-Mix, Annette +8 more
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Structural determinants of Arabidopsis thaliana Hyponastic leaves 1 function in vivo. [PDF]
PLoS ONE, 2014 MicroRNAs have turned out to be important regulators of gene expression. These molecules originate from longer transcripts that are processed by ribonuclease III (RNAse III) enzymes. Dicer proteins are essential RNAse III enzymes that are involved in the
Paula Burdisso +5 more
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Description Generation using Variational Auto-Encoders for precursor microRNA [PDF]
arXiv, 2023 Micro RNAs (miRNA) are a type of non-coding RNA, which are involved in gene regulation and can be associated with diseases such as cancer, cardiovascular and neurological diseases. As such, identifying the entire genome of miRNA can be of great relevance.
arxiv
Systematic identification of abundant A-to-I editing sites in the human transcriptome [PDF]
Nature Biotechnology 22, 1001-1005 (2004), 2004 RNA editing by members of the double-stranded RNA-specific ADAR family leads to site-specific conversion of adenosine to inosine (A-to-I) in precursor messenger RNAs. Editing by ADARs is believed to occur in all metazoa, and is essential for mammalian development.
arxiv +1 more source
Towards RNA life on Early Earth: From atmospheric HCN to biomolecule production in warm little ponds [PDF]
, 2022 The origin of life on Earth involves the early appearance of an information-containing molecule such as RNA. The basic building blocks of RNA could have been delivered by carbon-rich meteorites, or produced in situ by processes beginning with the synthesis of hydrogen cyanide (HCN) in the early Earth's atmosphere.
arxiv +1 more source
Pseudouridylation of yeast ribosomal precursor RNA
Nucleic Acids Research, 1979 The pseudouridylation of ribosomal RNA of Saccharomyces carlsbergensis was investigated with respect to its timing during the maturation of rRNA and its sequence specificity. Analysis of 37-S RNA, the common precursor to 17-S, 5.8-S and 26-S rRNA and most probably the primary ribosomal transcript, shows that this RNA molecule contains already most if ...
Reindert C. Brand +3 more
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Hfq and RNase R Mediate rRNA Processing and Degradation in a Novel RNA Quality Control Process
mBio, 2020 RNA quality control pathways are critical for cell survival. Here, we describe a new surveillance process involved in the degradation of highly structured and stable ribosomal RNAs.
Ricardo F. dos Santos +4 more
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