Results 11 to 20 of about 8,539,258 (300)

Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]

open access: yes, 2010
For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core   +3 more sources

A splicing-dependent transcriptional checkpoint associated with prespliceosome formation [PDF]

open access: yes, 2014
There is good evidence for functional interactions between splicing and transcription in eukaryotes, but how and why these processes are coupled remain unknown.
Chathoth, Keerthi T   +3 more
core   +1 more source

3’ Rapid Amplification of cDNA Ends (3’ RACE) Using Arabidopsis Samples

open access: yesBio-Protocol, 2015
Production of functional eukaryotic RNA is a very elaborate process that involves a complex interplay between transcription and various RNA processing activities, including splicing, 5’ capping, and 3’ cleavage and polyadenylation (Bentley, 2014 ...
Encarnación Rodríguez-Cazorla   +6 more
doaj   +1 more source

Transcriptional termination enhances protein expression in human cells [PDF]

open access: yes, 2009
Transcriptional termination of mammalian RNA polymerase II (Pol II) requires a poly(A) (pA) signal and, often, a downstream terminator sequence. Termination is triggered following recognition of the pA signal by Pol II and subsequent pre-mRNA cleavage ...
Proudfoot, Nicholas J   +4 more
core   +1 more source

Quantitative Analysis of RNA Editing at Specific Sites in Plant Mitochondria or Chloroplasts Using DNA Sequencing

open access: yesBio-Protocol, 2021
Cytidine-to-uridine (C-to-U) RNA editing is one of the most important post-transcriptional RNA processing in plant mitochondria and chloroplasts. Several techniques have been developed to detect the RNA editing efficiency in plant mitochondria and ...
Yang Yang, Weixing Shan
doaj   +1 more source

Post-transcriptional control of nuclear-encoded cytochrome oxidase subunits in Trypanosoma brucei:evidence for genome-wide conservation of life-cycle stage-specific regulatory elements [PDF]

open access: yes, 2006
Trypanosomes represent an excellent model for the post-transcriptional regulation of gene expression because their genome is organized into polycistronic transcription units.
Katelyn Fenn   +10 more
core   +1 more source

Drosophila as a Model for Assessing the Function of RNA-Binding Proteins during Neurogenesis and Neurological Disease

open access: yesJournal of Developmental Biology, 2018
An outstanding question in developmental neurobiology is how RNA processing events contribute to the regulation of neurogenesis. RNA processing events are increasingly recognized as playing fundamental roles in regulating multiple developmental events ...
Eugenia C. Olesnicky, Ethan G. Wright
doaj   +1 more source

A global screening identifies chromatin-enriched RNA-binding proteins and the transcriptional regulatory activity of QKI5 during monocytic differentiation

open access: yesGenome Biology, 2021
Background Cellular RNA-binding proteins (RBPs) have multiple roles in post-transcriptional control, and some are shown to bind DNA. However, the global localization and the general chromatin-binding ability of RBPs are not well-characterized and remain ...
Yue Ren   +16 more
doaj   +1 more source

Dynamic signal processing by ribozyme-mediated RNA circuits to control gene expression [PDF]

open access: yes, 2014
Organisms have different circuitries that allow converting signal molecule levels to changes in gene expression. An important challenge in synthetic biology involves the de novo design of RNA modules enabling dynamic signal processing in live cells. This
Satya Prakash   +21 more
core   +1 more source

Investigation of RNA-induced gene silencing in the fission yeast Schizosaccharomyces pombe [PDF]

open access: yes, 2007
PhDRNA interference (RNAi) is a gene regulating system to which can silence genes at both transcriptional and post-transcriptional levels. In this thesis, a ura4-based RNAi selective assay was developed in the fission yeast Schizosaccharomyces pombe ...
Wang, Huan
core   +4 more sources

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