Results 11 to 20 of about 442,476 (336)
Post-transcriptional gene regulation by mRNA modifications
Nature Reviews Molecular Cell Biology, 2016 B. Zhao, I. A. Roundtree, Chuan He
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Post‐transcriptional regulation of polycistronic microRNAs
Wiley Interdisciplinary Reviews - RNA, 2022 An important proportion of microRNA (miRNA) genes tend to lie close to each other within animal genomes. Such genomic organization is generally referred to as miRNA clusters.
M. Vilimova, S. Pfeffer
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The Splice of Life: Does RNA Processing Have a Role in HIV-1 Persistence?
Viruses, 2021 Antiretroviral therapy (ART) suppresses HIV-1 replication but does not eradicate the virus. Persistence of HIV-1 latent reservoirs in ART-treated individuals is considered the main obstacle to achieving an HIV-1 cure.
Alexander O. Pasternak, Ben Berkhout
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Single Molecule Imaging In Vivo Determines Post-Transcriptional RNA Processing Dynamics [PDF]
Biophysical Journal, 2014 The synthesis and splicing of pre-mRNA to form completed transcripts requires coordination between two large multi-subunit complexes (the RNA polymerase and the spliceosome). Using dual color single molecule RNA imaging in living human cells, we previously observed kinetic competition during the transcription cycle which resulted in both co- and post ...
Ferguson, Matthew L. +5 more
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RNA-binding proteins in tumor progression
Journal of Hematology & Oncology, 2020 RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and important biological functions. They are critical to maintain the transcriptome through post-transcriptionally controlling the processing and transportation of RNA ...
Hai Qin +6 more
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HibeRNAtion: HIV-1 RNA Metabolism and Viral Latency
Frontiers in Cellular and Infection Microbiology, 2022 HIV-1 infection remains non-curative due to the latent reservoir, primarily a small pool of resting memory CD4+ T cells bearing replication-competent provirus.
Raquel Crespo +4 more
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Regulation of RNA processing and degradation in bacteria.
Biochimica et Biophysica Acta. Gene Regulatory Mechanisms, 2020 Messenger RNA processing and decay is a key mechanism to control gene expression at the post-transcriptional level in response to ever-changing environmental conditions.
A. Trinquier +3 more
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RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]
, 2016 Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan +17 more
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Computational prediction of RNA structural motifs involved in posttranscriptional regulatory processes [PDF]
Proceedings of the National Academy of Sciences, 2008 Messenger RNA molecules are tightly regulated, mostly through interactions with proteins and other RNAs, but the mechanisms that confer the specificity of such interactions are poorly understood. It is clear, however, that this specificity is determined by both the nucleotide sequence and secondary structure of the mRNA.
Rabani, Michal +2 more
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Complex RNA metabolism in the chloroplast: an update on the psbB operon [PDF]
, 2012 Expression of most plastid genes involves multiple post-transcriptional processing events, such as splicing, editing, and intercistronic processing. The latter involves the formation of mono-, di-, and multicistronic transcripts, which can further be ...
Jörg Meurer, Rhea Stoppel
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