Results 11 to 20 of about 8,539,258 (300)
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core +3 more sources
A splicing-dependent transcriptional checkpoint associated with prespliceosome formation [PDF]
There is good evidence for functional interactions between splicing and transcription in eukaryotes, but how and why these processes are coupled remain unknown.
Chathoth, Keerthi T +3 more
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3’ Rapid Amplification of cDNA Ends (3’ RACE) Using Arabidopsis Samples
Production of functional eukaryotic RNA is a very elaborate process that involves a complex interplay between transcription and various RNA processing activities, including splicing, 5’ capping, and 3’ cleavage and polyadenylation (Bentley, 2014 ...
Encarnación Rodríguez-Cazorla +6 more
doaj +1 more source
Transcriptional termination enhances protein expression in human cells [PDF]
Transcriptional termination of mammalian RNA polymerase II (Pol II) requires a poly(A) (pA) signal and, often, a downstream terminator sequence. Termination is triggered following recognition of the pA signal by Pol II and subsequent pre-mRNA cleavage ...
Proudfoot, Nicholas J +4 more
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Cytidine-to-uridine (C-to-U) RNA editing is one of the most important post-transcriptional RNA processing in plant mitochondria and chloroplasts. Several techniques have been developed to detect the RNA editing efficiency in plant mitochondria and ...
Yang Yang, Weixing Shan
doaj +1 more source
Post-transcriptional control of nuclear-encoded cytochrome oxidase subunits in Trypanosoma brucei:evidence for genome-wide conservation of life-cycle stage-specific regulatory elements [PDF]
Trypanosomes represent an excellent model for the post-transcriptional regulation of gene expression because their genome is organized into polycistronic transcription units.
Katelyn Fenn +10 more
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An outstanding question in developmental neurobiology is how RNA processing events contribute to the regulation of neurogenesis. RNA processing events are increasingly recognized as playing fundamental roles in regulating multiple developmental events ...
Eugenia C. Olesnicky, Ethan G. Wright
doaj +1 more source
Background Cellular RNA-binding proteins (RBPs) have multiple roles in post-transcriptional control, and some are shown to bind DNA. However, the global localization and the general chromatin-binding ability of RBPs are not well-characterized and remain ...
Yue Ren +16 more
doaj +1 more source
Dynamic signal processing by ribozyme-mediated RNA circuits to control gene expression [PDF]
Organisms have different circuitries that allow converting signal molecule levels to changes in gene expression. An important challenge in synthetic biology involves the de novo design of RNA modules enabling dynamic signal processing in live cells. This
Satya Prakash +21 more
core +1 more source
Investigation of RNA-induced gene silencing in the fission yeast Schizosaccharomyces pombe [PDF]
PhDRNA interference (RNAi) is a gene regulating system to which can silence genes at both transcriptional and post-transcriptional levels. In this thesis, a ura4-based RNAi selective assay was developed in the fission yeast Schizosaccharomyces pombe ...
Wang, Huan
core +4 more sources

