Yeast Nrd1, Nab3, and Sen1 transcriptome-wide binding maps suggest multiple roles in post-transcriptional RNA processing [PDF]
RNA, 2011 RNA polymerase II transcribes both coding and noncoding genes, and termination of these different classes of transcripts is facilitated by different sets of termination factors. Pre-mRNAs are terminated through a process that is coupled to the cleavage/polyadenylation machinery, and noncoding RNAs in the yeast Saccharomyces cerevisiae are terminated ...
Nuttara, Jamonnak +5 more
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RNA-specific ribonucleotidyl transferases [PDF]
, 2007 RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W. +3 more
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An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites
npj Aging and Mechanisms of Disease, 2017 Muscle degeneration: RNA structures as modulator of muscle function Transcriptional and post-transcriptional regulation of gene expression has a fundamental role in shaping the protein landscape.
Tooba Abbassi-Daloii +6 more
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The RNA Polymerase II-associated factor 1 complex represses small-RNA-mediated heterochromatin formation and gene silencing [PDF]
, 2015 RNAi interference (RNAi) is a highly conserved regulatory mechanism employed by almost all Eukaryotes. With RNAi organisms can modulate the expression of endogenous genes and protect the integrity and identity of their genomes.
Kowalik, Katarzyna Maria
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Transcription Is Just the Beginning of Gene Expression Regulation: The Functional Significance of RNA-Binding Proteins to Post-transcriptional Processes in Plants [PDF]
Plant and Cell Physiology, 2019 AbstractPlants have developed sophisticated mechanisms to compensate and respond to ever-changing environmental conditions. Research focus in this area has recently shifted towards understanding the post-transcriptional mechanisms that contribute to RNA transcript maturation, abundance and function as key regulatory steps in allowing plants to properly
Brian D Gregory +2 more
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The retrovirus RNA trafficking granule: from birth to maturity
Retrovirology, 2006 Post-transcriptional events in the life of an RNA including RNA processing, transport, translation and metabolism are characterized by the regulated assembly of multiple ribonucleoprotein (RNP) complexes.
Mouland Andrew J +2 more
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RNA Metabolism Guided by RNA Modifications: The Role of SMUG1 in rRNA Quality Control
Biomolecules, 2021 RNA modifications are essential for proper RNA processing, quality control, and maturation steps. In the last decade, some eukaryotic DNA repair enzymes have been shown to have an ability to recognize and process modified RNA substrates and thereby ...
Lisa Lirussi +5 more
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Frontiers in Molecular Neuroscience, 2018 Neurons are morphologically complex cells that rely on the compartmentalization of protein expression to develop and maintain their extraordinary cytoarchitecture. This formidable task is achieved, at least in part, by targeting mRNA to subcellular compartments where they are rapidly translated.
Andreassi, C, Crerar, H, Riccio, A
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Production of Viral mRNA in Adenovirus-Transformed Cells by the Post-Transcriptional Processing of Heterogeneous Nuclear RNA Containing Viral and Cell Sequences [PDF]
Journal of Virology, 1973 Adenovirus 2-transformed cells contain virus-specific sequences which are covalently linked to cell-specific RNA sequences in heterogeneous nuclear RNA (HnRNA) molecules larger than 45 S . Virus sequences are identified by hybridization to viral DNA, and the cell sequences are detected by hybridization to cellular ...
R, Wall, J, Weber, Z, Gage, J E, Darnell
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Functional characterization of Ysh1p, the yeast endonuclease involved in 3" end processing and in transcription termination of RNA polymerase II transcripts [PDF]
, 2008 Eukaryotic RNA polymerase II (RNAP II) is involved in the synthesis of two major classes of transcripts: messenger RNAs (mRNAs) and small nuclear and small nucleolar RNAs.
Garas, Monika
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