RNA Metabolism Guided by RNA Modifications: The Role of SMUG1 in rRNA Quality Control
Biomolecules, 2021 RNA modifications are essential for proper RNA processing, quality control, and maturation steps. In the last decade, some eukaryotic DNA repair enzymes have been shown to have an ability to recognize and process modified RNA substrates and thereby ...
Lisa Lirussi +5 more
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Post-transcriptional control of miRNA biogenesis
RNA: A publication of the RNA Society, 2018 MicroRNAs (miRNAs) are important regulators of gene expression that bind complementary target mRNAs and repress their expression. Precursor miRNA molecules undergo nuclear and cytoplasmic processing events, carried out by the endoribonucleases DROSHA and
G. Michlewski, J. Cáceres
semanticscholar +1 more source
The Nefarious Nexus of Noncoding RNAs in Cancer [PDF]
, 2018 The past decade has witnessed enormous progress, which has seen the noncoding RNAs (ncRNAs) turn from the so called dark matter RNA to critical functional molecules, influencing most physiological processes in development and disease contexts.
Anastasiadou, Eleni +3 more
core +1 more source
An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites
npj Aging and Mechanisms of Disease, 2017 Muscle degeneration: RNA structures as modulator of muscle function Transcriptional and post-transcriptional regulation of gene expression has a fundamental role in shaping the protein landscape.
Tooba Abbassi-Daloii +6 more
doaj +1 more source
IARA: a complete and curated atlas of the biogenesis of spliceosome machinery during RNA splicing
Life Science Alliance, 2023 The online atlas IARA is a curated and updated resource with genetic and molecular data on the biogenesis of human spliceosome machinery involved in RNA splicing.
Kelren S Rodrigues +4 more
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The changing role of cell culture in the generation of transgenic livestock [PDF]
, 1999 Transgenesis may allow the generation of farm animals with altered phenotype, animal models for research and animal bioreactors. Although such animals have been produced, the time and expense involved in generating transgenic livestock and then ...
Farini, E, Webster, J, Whitelaw, C B
core +1 more source
The retrovirus RNA trafficking granule: from birth to maturity
Retrovirology, 2006 Post-transcriptional events in the life of an RNA including RNA processing, transport, translation and metabolism are characterized by the regulated assembly of multiple ribonucleoprotein (RNP) complexes.
Mouland Andrew J +2 more
doaj +1 more source
Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]
, 2017 Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani +5 more
core +1 more source
Traffic into silence: endomembranes and post-transcriptional RNA silencing. [PDF]
, 2014 microRNAs (miRNAs) and small interfering RNAs (siRNAs) are small RNAs that repress gene expression at the post-transcriptional level in plants and animals. Small RNAs guide Argonaute-containing RNA-induced silencing complexes to target RNAs in a sequence-
Chen, Xuemei +2 more
core +3 more sources
Production of Viral mRNA in Adenovirus-Transformed Cells by the Post-Transcriptional Processing of Heterogeneous Nuclear RNA Containing Viral and Cell Sequences [PDF]
Journal of Virology, 1973 Adenovirus 2-transformed cells contain virus-specific sequences which are covalently linked to cell-specific RNA sequences in heterogeneous nuclear RNA (HnRNA) molecules larger than 45 S . Virus sequences are identified by hybridization to viral DNA, and the cell sequences are detected by hybridization to cellular ...
R, Wall, J, Weber, Z, Gage, J E, Darnell
openaire +2 more sources