Alternative cleavage and polyadenylation: key regulatory mechanisms in health and disease. [PDF]
Zhang Y, Huang Z, Lu W, Liu Z.
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Epigenetic modifications in the murine liver upon depletion of transcriptional coregulator host cell factor 1. [PDF]
Kaushal S+5 more
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Transcriptomic analysis reveals shared deregulated neutrophil responses in COVID-19 and idiopathic pulmonary fibrosis. [PDF]
Divolis G+6 more
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Sperm-borne mRNAs: potential roles in zygote genome activation and epigenetic inheritance. [PDF]
González B, González CR.
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Specialised RNA decay fine-tunes monogenic antigen expression in African trypanosomes
Lansink LIM+5 more
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The goal of our workshop is to introduce some recent work in the area of post-transcriptional regulation to a wider computational community, discuss some of the unique computational problems faced in this area, and to present some preliminary solutions ...
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Timing effciency in small-RNA-regulated post-transcriptional processes
Physical Review E, 2020Gene regulation in a cellular environment is a stochastic phenomenon leading to a large variability in mRNAs and protein numbers that are often produced in bursts. The regulation leading to varied protein dynamics can be ascribed to transcriptional or post-transcriptional mechanisms.
Kuheli Biswas, Anandamohan Ghosh
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Viral RNA in the cytoplasm of SV40-transformed mouse cells: Post-transcriptional processing
Virology, 1976Abstract The virus-specific RNA present in the cytoplasmic and total cellular RNA of three standard and three flat lines of SV40-transformed mouse cells has been examined. The results using separated strands of the entire viral genome as hybridization probes indicate that extensive processing or selection of viral-specific RNA sequences occurs in ...
Leong, J C, Smith, H S, Goodman, H M
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Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells
Biochemical Society Transactions, 2004In HSV-1 (herpes simplex virus 1)-infected cells, the UL41 gene product carried with the virion has been shown to mediate the degradation of mRNA, leading to the shut-off of cellular protein synthesis. Analysis of the RNAs accumulating in cells infected with HSV-1 revealed the accumulation of RNAs encoding numerous cellular proteins both associated ...
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