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Abstract Wed043: Genetic Variants in RNA Binding Motif Protein 20 Cause Early-onset Heart Failure by Disrupting Post-Transcriptional Process

Circulation Research
Introduction: RNA binding motif protein 20 (RBM20) cardiomyopathy is a severe form of dilated cardiomyopathy (DCM), leading to early-onset heart failure (HF). The condition has been linked to cytoplasmic RBM20 granules induced by RBM20 genetic variants, although the precise mechanism remains unclear.
Yanghai Zhang   +6 more
openaire   +1 more source

A tale of non-canonical tails: gene regulation by post-transcriptional RNA tailing

Nature Reviews Molecular Cell Biology, 2020
Sha Yu, V Narry Kim, Kim V Narry
exaly  

The emerging biology of RNA post-transcriptional modifications

RNA Biology, 2017
Sigrid Nachtergaële, Chuan He
exaly  

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