Results 271 to 280 of about 203,837 (307)
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Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells
Biochemical Society Transactions, 2004In HSV-1 (herpes simplex virus 1)-infected cells, the UL41 gene product carried with the virion has been shown to mediate the degradation of mRNA, leading to the shut-off of cellular protein synthesis. Analysis of the RNAs accumulating in cells infected with HSV-1 revealed the accumulation of RNAs encoding numerous cellular proteins both associated ...
B, Taddeo, A, Esclatine, B, Roizman
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Viral RNA in the cytoplasm of SV40-transformed mouse cells: Post-transcriptional processing
Virology, 1976Abstract The virus-specific RNA present in the cytoplasmic and total cellular RNA of three standard and three flat lines of SV40-transformed mouse cells has been examined. The results using separated strands of the entire viral genome as hybridization probes indicate that extensive processing or selection of viral-specific RNA sequences occurs in ...
Leong, J C, Smith, H S, Goodman, H M
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Journal of Molecular Biology, 1974
Abstract An RNA fraction in HeLa cell mitochondria has previously been shown to contain a small polyadenylic acid sequence (56 nucleotides) and to behave like messenger RNA. This fraction can be resolved into approximately eight distinct species which may be the messages for the mitochondrial-specified proteins.
M, Hirsch, S, Penman
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Abstract An RNA fraction in HeLa cell mitochondria has previously been shown to contain a small polyadenylic acid sequence (56 nucleotides) and to behave like messenger RNA. This fraction can be resolved into approximately eight distinct species which may be the messages for the mitochondrial-specified proteins.
M, Hirsch, S, Penman
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Transgenic Research, 2009
A tissue-specific transgenic model was employed to test the effects of intron and vector sequences on transgene expression in zebrafish after microinjection. In this model, the 2.3 kb promoter taken from the 5' upstream region of the transcription initiation site of keratin 4 (krt4) was used to drive the enhanced green fluorescence protein (EGFP ...
Sumantra, Chatterjee +3 more
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A tissue-specific transgenic model was employed to test the effects of intron and vector sequences on transgene expression in zebrafish after microinjection. In this model, the 2.3 kb promoter taken from the 5' upstream region of the transcription initiation site of keratin 4 (krt4) was used to drive the enhanced green fluorescence protein (EGFP ...
Sumantra, Chatterjee +3 more
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Cancer Research, 2021
Abstract APOBEC3G is a cytidine deaminase with a well-characterized anti-viral role against HIV and other retroviruses. Its deaminase activity yields G to A edits in ssDNA to disrupt viral coding sequences and inhibits cDNA production during reverse transcription.
Joanna D. Wardyn +11 more
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Abstract APOBEC3G is a cytidine deaminase with a well-characterized anti-viral role against HIV and other retroviruses. Its deaminase activity yields G to A edits in ssDNA to disrupt viral coding sequences and inhibits cDNA production during reverse transcription.
Joanna D. Wardyn +11 more
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Molecular and General Genetics MGG, 1998
The importance of Lactococcus lactis biovar diacetylactis (L. diacetylactis) in the dairy industry is due to its ability to produce aroma compounds, such as acetoin and diacetyl, from citrate. The first step in citrate utilization is its uptake by the cells. In L. diacetylactis, the citrate transport system is encoded by the citQRP operon.
D, Drider +3 more
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The importance of Lactococcus lactis biovar diacetylactis (L. diacetylactis) in the dairy industry is due to its ability to produce aroma compounds, such as acetoin and diacetyl, from citrate. The first step in citrate utilization is its uptake by the cells. In L. diacetylactis, the citrate transport system is encoded by the citQRP operon.
D, Drider +3 more
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Journal of Theoretical Biology, 1987
We propose that the human c-myc gene expression is regulated by a post-transcriptional mechanism based on the formation of a hairpin structure between c-myc mRNA exons 1 and 2. This structure could be rapidly processed by a hypothetical double stranded RNAse, removing the 5' end segment of the c-myc mRNA having the cap site.
P, Gariglio +3 more
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We propose that the human c-myc gene expression is regulated by a post-transcriptional mechanism based on the formation of a hairpin structure between c-myc mRNA exons 1 and 2. This structure could be rapidly processed by a hypothetical double stranded RNAse, removing the 5' end segment of the c-myc mRNA having the cap site.
P, Gariglio +3 more
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Journal of Cell Science, 1997
ABSTRACT The identification of a gene encoding concomitantly a nuclear protein and an intrinsic centrosomal protein further emphasizes the close and presumably developmental relationship between the cell nucleus and the centro-some. Screening of a murine RNA-based cDNA library with an antiserum to a centrosomal protein and rescreening ...
C, Petzelt +5 more
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ABSTRACT The identification of a gene encoding concomitantly a nuclear protein and an intrinsic centrosomal protein further emphasizes the close and presumably developmental relationship between the cell nucleus and the centro-some. Screening of a murine RNA-based cDNA library with an antiserum to a centrosomal protein and rescreening ...
C, Petzelt +5 more
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RNA Processing and Other Post-Transcriptional Modifications
1982RNA molecules play a central part in cell metabolism, either by directing the synthesis of proteins or functioning as essential components of the proteinsynthesising machinery. A detailed knowledge of their structure and metabolism is, therefore, an essential pre-requisite for an understanding of the control of protein synthesis.
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Molecular Cell
Cys2-His2 zinc-finger proteins (C2H2-ZNFs) constitute the largest class of DNA-binding transcription factors (TFs) yet remain largely uncharacterized. Although certain family members, e.g., GTF3A, have been shown to bind both DNA and RNA, the extent to which C2H2-ZNFs interact with-and regulate-RNA-associated processes is not known.
Syed, Nabeel-Shah +14 more
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Cys2-His2 zinc-finger proteins (C2H2-ZNFs) constitute the largest class of DNA-binding transcription factors (TFs) yet remain largely uncharacterized. Although certain family members, e.g., GTF3A, have been shown to bind both DNA and RNA, the extent to which C2H2-ZNFs interact with-and regulate-RNA-associated processes is not known.
Syed, Nabeel-Shah +14 more
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