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Molecular Cell
Cys2-His2 zinc-finger proteins (C2H2-ZNFs) constitute the largest class of DNA-binding transcription factors (TFs) yet remain largely uncharacterized. Although certain family members, e.g., GTF3A, have been shown to bind both DNA and RNA, the extent to which C2H2-ZNFs interact with-and regulate-RNA-associated processes is not known.
Syed, Nabeel-Shah +14 more
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Cys2-His2 zinc-finger proteins (C2H2-ZNFs) constitute the largest class of DNA-binding transcription factors (TFs) yet remain largely uncharacterized. Although certain family members, e.g., GTF3A, have been shown to bind both DNA and RNA, the extent to which C2H2-ZNFs interact with-and regulate-RNA-associated processes is not known.
Syed, Nabeel-Shah +14 more
openaire +2 more sources
Circulation Research
Introduction: RNA binding motif protein 20 (RBM20) cardiomyopathy is a severe form of dilated cardiomyopathy (DCM), leading to early-onset heart failure (HF). The condition has been linked to cytoplasmic RBM20 granules induced by RBM20 genetic variants, although the precise mechanism remains unclear.
Yanghai Zhang +6 more
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Introduction: RNA binding motif protein 20 (RBM20) cardiomyopathy is a severe form of dilated cardiomyopathy (DCM), leading to early-onset heart failure (HF). The condition has been linked to cytoplasmic RBM20 granules induced by RBM20 genetic variants, although the precise mechanism remains unclear.
Yanghai Zhang +6 more
openaire +1 more source
Diverse RNA processing pathways important for post-transcriptional gene regulation
2010Cis-acting elements in 3' untranslated regions (UTRs) of mRNAs are crucial to the regulation of gene expression. Animal microRNAs (miRNAs) each target hundreds of mRNAs, which are recognized by pairing to nucleotides 2-7 of the miRNA. MicroRNAs mature through sequential RNase III cleavage of characteristic stem-loop precursors.
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RNA-Binding Proteins as Critical Post-Transcriptional Regulators of Cardiac Regeneration
International Journal of Molecular Sciences, 2023Deli Shi
exaly
A tale of non-canonical tails: gene regulation by post-transcriptional RNA tailing
Nature Reviews Molecular Cell Biology, 2020Vic Narry Kim, Sha Yu
exaly
MOLECULAR MECHANISMS OF CALCITONIN GENE TRANSCRIPTION AND POST-TRANSCRIPTIONAL RNA PROCESSING
1993SARA PELEG +2 more
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Post-transcriptional control by RNA-binding proteins in diabetes and its related complications
Frontiers in Physiology, 2022Ji Hu, Hong-Hong Zhang
exaly