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Post-transcriptional addition of polyadenylic acid to mitochondrial RNA by a cordycepin-insensitive process

Journal of Molecular Biology, 1974
Abstract An RNA fraction in HeLa cell mitochondria has previously been shown to contain a small polyadenylic acid sequence (56 nucleotides) and to behave like messenger RNA. This fraction can be resolved into approximately eight distinct species which may be the messages for the mitochondrial-specified proteins.
Martin Hirsch, Sheldon Penman
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Abstract 2443: APOBEC3G is a sex-specific determinant of post-transcriptional RNA processing and survival in diffuse large B-cell lymphoma

Cancer Research, 2021
Abstract APOBEC3G is a cytidine deaminase with a well-characterized anti-viral role against HIV and other retroviruses. Its deaminase activity yields G to A edits in ssDNA to disrupt viral coding sequences and inhibits cDNA production during reverse transcription.
Henry Yang   +11 more
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The role of post-transcriptional RNA processing and plasmid vector sequences on transient transgene expression in zebrafish

Transgenic Research, 2009
A tissue-specific transgenic model was employed to test the effects of intron and vector sequences on transgene expression in zebrafish after microinjection. In this model, the 2.3 kb promoter taken from the 5' upstream region of the transcription initiation site of keratin 4 (krt4) was used to drive the enhanced green fluorescence protein (EGFP ...
Sumantra Chatterjee   +5 more
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RNA processing is involved in the post-transcriptional control of the citQRP operon from Lactococcus lactis biovar diacetylactis

Molecular and General Genetics MGG, 1998
The importance of Lactococcus lactis biovar diacetylactis (L. diacetylactis) in the dairy industry is due to its ability to produce aroma compounds, such as acetoin and diacetyl, from citrate. The first step in citrate utilization is its uptake by the cells. In L. diacetylactis, the citrate transport system is encoded by the citQRP operon.
Djamel Drider   +3 more
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The post-transcriptional life of mammalian mitochondrial RNA.

Biochemical Journal, 2012
Mammalian mitochondria contain their own genome that encodes mRNAs for thirteen essential subunits of the complexes performing oxidative phosphorylation as well as the RNA components (two rRNAs and 22 tRNAs) needed for their translation in mitochondria ...
J. Rorbach, M. Minczuk
semanticscholar   +1 more source

Theoretical model for the post-transcriptional regulation of the human c-myc gene expression, involving double-stranded RNA processing

Journal of Theoretical Biology, 1987
We propose that the human c-myc gene expression is regulated by a post-transcriptional mechanism based on the formation of a hairpin structure between c-myc mRNA exons 1 and 2. This structure could be rapidly processed by a hypothetical double stranded RNAse, removing the 5' end segment of the c-myc mRNA having the cap site.
Patricio Gariglio   +3 more
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Gene expression control by selective RNA processing and stabilization in bacteria.

FEMS Microbiology Letters, 2013
RNA maturation is a key event regulating genes at post-transcriptional level. In bacteria, it is employed to adjust the amounts of proteins and functional RNAs, often in response to environmental constraints. During the process of RNA maturation, enzymes
T. Rochat, P. Bouloc, F. Repoila
semanticscholar   +1 more source

The centrosomal protein centrosomin A and the nuclear protein centrosomin B derive from one gene by post-transcriptional processes involving RNA editing

Journal of Cell Science, 1997
ABSTRACT The identification of a gene encoding concomitantly a nuclear protein and an intrinsic centrosomal protein further emphasizes the close and presumably developmental relationship between the cell nucleus and the centro-some. Screening of a murine RNA-based cDNA library with an antiserum to a centrosomal protein and rescreening ...
Gaby Joswig   +5 more
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RNA Processing and Other Post-Transcriptional Modifications

1982
RNA molecules play a central part in cell metabolism, either by directing the synthesis of proteins or functioning as essential components of the proteinsynthesising machinery. A detailed knowledge of their structure and metabolism is, therefore, an essential pre-requisite for an understanding of the control of protein synthesis.
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C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes

Molecular Cell
Cys2-His2 zinc-finger proteins (C2H2-ZNFs) constitute the largest class of DNA-binding transcription factors (TFs) yet remain largely uncharacterized. Although certain family members, e.g., GTF3A, have been shown to bind both DNA and RNA, the extent to which C2H2-ZNFs interact with-and regulate-RNA-associated processes is not known.
Syed, Nabeel-Shah   +14 more
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