Results 301 to 310 of about 376,369 (323)
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Journal of Molecular Biology, 1974
Abstract An RNA fraction in HeLa cell mitochondria has previously been shown to contain a small polyadenylic acid sequence (56 nucleotides) and to behave like messenger RNA. This fraction can be resolved into approximately eight distinct species which may be the messages for the mitochondrial-specified proteins.
Martin Hirsch, Sheldon Penman
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Abstract An RNA fraction in HeLa cell mitochondria has previously been shown to contain a small polyadenylic acid sequence (56 nucleotides) and to behave like messenger RNA. This fraction can be resolved into approximately eight distinct species which may be the messages for the mitochondrial-specified proteins.
Martin Hirsch, Sheldon Penman
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Cancer Research, 2021
Abstract APOBEC3G is a cytidine deaminase with a well-characterized anti-viral role against HIV and other retroviruses. Its deaminase activity yields G to A edits in ssDNA to disrupt viral coding sequences and inhibits cDNA production during reverse transcription.
Henry Yang+11 more
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Abstract APOBEC3G is a cytidine deaminase with a well-characterized anti-viral role against HIV and other retroviruses. Its deaminase activity yields G to A edits in ssDNA to disrupt viral coding sequences and inhibits cDNA production during reverse transcription.
Henry Yang+11 more
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Transgenic Research, 2009
A tissue-specific transgenic model was employed to test the effects of intron and vector sequences on transgene expression in zebrafish after microinjection. In this model, the 2.3 kb promoter taken from the 5' upstream region of the transcription initiation site of keratin 4 (krt4) was used to drive the enhanced green fluorescence protein (EGFP ...
Sumantra Chatterjee+5 more
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A tissue-specific transgenic model was employed to test the effects of intron and vector sequences on transgene expression in zebrafish after microinjection. In this model, the 2.3 kb promoter taken from the 5' upstream region of the transcription initiation site of keratin 4 (krt4) was used to drive the enhanced green fluorescence protein (EGFP ...
Sumantra Chatterjee+5 more
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Molecular and General Genetics MGG, 1998
The importance of Lactococcus lactis biovar diacetylactis (L. diacetylactis) in the dairy industry is due to its ability to produce aroma compounds, such as acetoin and diacetyl, from citrate. The first step in citrate utilization is its uptake by the cells. In L. diacetylactis, the citrate transport system is encoded by the citQRP operon.
Djamel Drider+3 more
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The importance of Lactococcus lactis biovar diacetylactis (L. diacetylactis) in the dairy industry is due to its ability to produce aroma compounds, such as acetoin and diacetyl, from citrate. The first step in citrate utilization is its uptake by the cells. In L. diacetylactis, the citrate transport system is encoded by the citQRP operon.
Djamel Drider+3 more
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The post-transcriptional life of mammalian mitochondrial RNA.
Biochemical Journal, 2012Mammalian mitochondria contain their own genome that encodes mRNAs for thirteen essential subunits of the complexes performing oxidative phosphorylation as well as the RNA components (two rRNAs and 22 tRNAs) needed for their translation in mitochondria ...
J. Rorbach, M. Minczuk
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Journal of Theoretical Biology, 1987
We propose that the human c-myc gene expression is regulated by a post-transcriptional mechanism based on the formation of a hairpin structure between c-myc mRNA exons 1 and 2. This structure could be rapidly processed by a hypothetical double stranded RNAse, removing the 5' end segment of the c-myc mRNA having the cap site.
Patricio Gariglio+3 more
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We propose that the human c-myc gene expression is regulated by a post-transcriptional mechanism based on the formation of a hairpin structure between c-myc mRNA exons 1 and 2. This structure could be rapidly processed by a hypothetical double stranded RNAse, removing the 5' end segment of the c-myc mRNA having the cap site.
Patricio Gariglio+3 more
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Gene expression control by selective RNA processing and stabilization in bacteria.
FEMS Microbiology Letters, 2013RNA maturation is a key event regulating genes at post-transcriptional level. In bacteria, it is employed to adjust the amounts of proteins and functional RNAs, often in response to environmental constraints. During the process of RNA maturation, enzymes
T. Rochat, P. Bouloc, F. Repoila
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Journal of Cell Science, 1997
ABSTRACT The identification of a gene encoding concomitantly a nuclear protein and an intrinsic centrosomal protein further emphasizes the close and presumably developmental relationship between the cell nucleus and the centro-some. Screening of a murine RNA-based cDNA library with an antiserum to a centrosomal protein and rescreening ...
Gaby Joswig+5 more
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ABSTRACT The identification of a gene encoding concomitantly a nuclear protein and an intrinsic centrosomal protein further emphasizes the close and presumably developmental relationship between the cell nucleus and the centro-some. Screening of a murine RNA-based cDNA library with an antiserum to a centrosomal protein and rescreening ...
Gaby Joswig+5 more
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RNA Processing and Other Post-Transcriptional Modifications
1982RNA molecules play a central part in cell metabolism, either by directing the synthesis of proteins or functioning as essential components of the proteinsynthesising machinery. A detailed knowledge of their structure and metabolism is, therefore, an essential pre-requisite for an understanding of the control of protein synthesis.
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Molecular Cell
Cys2-His2 zinc-finger proteins (C2H2-ZNFs) constitute the largest class of DNA-binding transcription factors (TFs) yet remain largely uncharacterized. Although certain family members, e.g., GTF3A, have been shown to bind both DNA and RNA, the extent to which C2H2-ZNFs interact with-and regulate-RNA-associated processes is not known.
Syed, Nabeel-Shah+14 more
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Cys2-His2 zinc-finger proteins (C2H2-ZNFs) constitute the largest class of DNA-binding transcription factors (TFs) yet remain largely uncharacterized. Although certain family members, e.g., GTF3A, have been shown to bind both DNA and RNA, the extent to which C2H2-ZNFs interact with-and regulate-RNA-associated processes is not known.
Syed, Nabeel-Shah+14 more
openaire +2 more sources