Results 251 to 260 of about 938,495 (334)

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

CRISPR-Cas9-based one-step multiplexed genome editing through optimizing guide RNA processing strategies in Pichia pastoris. [PDF]

Synth Syst Biotechnol
Chen K, Maimaitirexiati G, Zhang Q, Li Y, Liu X, Tang H, Gao X, Wang B, Yu T, Guo S.   +9 more
europepmc   +1 more source

Altered Proteolytic Processing of the Polymerase Polyprotein in RNA(-) Temperature Sensitive Mutants of Murine Coronavirus

, 1994
Susan C. Baker, Hongqiang Gao, Ralph S. Baric   +2 more
openalex   +1 more source

Transcripts That Increase the Processivity and Elongation Rate of RNA Polymerase [PDF]

, 1996
Rodney A. King, Sarbani Banik‐Maiti, Ding Jun Jin, Robert A. Weisberg   +3 more
openalex   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Virus-modified paraspeckle-like condensates are hubs for viral RNA processing and their formation drives genomic instability. [PDF]

Nat Commun
Harper KL, Harrington EM, Hayward C, Anene CA, Wongwiwat W, White RE, Whitehouse A.   +6 more
europepmc   +1 more source

Purification of the cleavage and polyadenylation factor involved in the 3'-processing of messenger RNA precursors.

, 1991
S. Bienroth, Elmar Wahle, Clemens Suter‐Crazzolara, Walter Keller   +3 more
openalex   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

The uS10c-BPG2 module mediates ribosomal RNA processing in chloroplast nucleoids. [PDF]

Nucleic Acids Res
Sun X, Singla-Rastogi M, Wang J, Zhao C, Wang X, Li P.   +5 more
europepmc   +1 more source

3' RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes.

, 1993
Gretchen Edwalds-Gilbert, John C. Prescott, Erik Falck-Pedersen   +2 more
openalex   +1 more source