Results 201 to 210 of about 1,457,994 (304)

Unveiling urethral cellular heterogeneity in menopause through single-nucleus RNA sequencing. [PDF]

Front Physiol
Mu J, Xiong J, Zhou S, Qin Z, Chen J, Guo H, Du G.   +6 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Sensitive, flexible, and affordable serum RNA sequencing for pathogen detection on the Oxford Nanopore platform. [PDF]

BMC Genomics
Selhorst P, Van Vyve E, Falconi-Agapito F, Mariën J, Ariën KK.   +4 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Genomic language model mitigates chimera artifacts in nanopore direct RNA sequencing. [PDF]

Nat Commun
Li Y, Wang TY, Guo Q, Ren Y, Lu X, Cao Q, Yang R.   +6 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Single-cell RNA sequencing revealed cell heterogeneity in sagittal suture mesenchyme. [PDF]

Front Cell Dev Biol
Ren C, Sun K, Wu R, Geng C, Chen J, Zhao H, Chen W.   +6 more
europepmc   +1 more source

Rare event detection using error-corrected DNA and RNA sequencing [PDF]

, 2018
Druley, Todd E, Tong, R. Spencer, Wong, Wing H, Young, Andrew L   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Coding and non-coding RNA sequencing during Thalassiosira gravida resting cell formation. [PDF]

Sci Data
Sepe RM, Orefice I, Di Marsico M, Montresor M, Romano G, Di Dato V, Greco S.   +6 more
europepmc   +1 more source