Results 21 to 30 of about 1,457,994 (304)
Single genome sequencing of near full-length HIV-1 RNA using a limiting dilution approach [PDF]
, 2019 Sequencing very long stretches of the HIV-1 genome can advance studies on virus evolution and in vivo recombination but remains technically challenging.
Demecheleer, Els +7 more
core +1 more source
rMAPS: RNA map analysis and plotting server for alternative exon regulation. [PDF]
, 2016 RNA-binding proteins (RBPs) play a critical role in the regulation of alternative splicing (AS), a prevalent mechanism for generating transcriptomic and proteomic diversity in eukaryotic cells.
Jung, Sungbo +4 more
core +2 more sources
RNA Sequencing and Analysis [PDF]
Cold Spring Harbor Protocols, 2015 RNA sequencing (RNA-Seq) uses the capabilities of high-throughput sequencing methods to provide insight into the transcriptome of a cell. Compared to previous Sanger sequencing- and microarray-based methods, RNA-Seq provides far higher coverage and greater resolution of the dynamic nature of the transcriptome.
Kimberly R, Kukurba +1 more
openaire +2 more sources
Metagenomes, metatranscriptomes and microbiomes of naturally decomposing deadwood
Scientific Data, 2021 Measurement(s) metagenomic data • metatranscriptomic data • microbiome • RNA-seq of total RNA Technology Type(s) DNA sequencing • RNA-seq of total RNA • amplicon sequencing • RNA sequencing Factor Type(s) time of decomposition Sample Characteristic ...
Vojtěch Tláskal +7 more
doaj +1 more source
Small RNA transcriptome analysis using parallel single-cell small RNA sequencing
Scientific Reports, 2023 miRNA and other forms of small RNAs are known to regulate many biological processes. Single-cell small RNA sequencing can be used to profile small RNAs of individual cells; however, limitations of efficiency and scale prevent its widespread application ...
Jia Li +4 more
doaj +1 more source
Integrative analysis revealed the molecular mechanism underlying RBM10‐mediated splicing regulation
EMBO Molecular Medicine, 2013 RBM10 encodes an RNA binding protein. Mutations in RBM10 are known to cause multiple congenital anomaly syndrome in male humans, the TARP syndrome. However, the molecular function of RBM10 is unknown.
Yongbo Wang +14 more
doaj +1 more source
G3: Genes, Genomes, Genetics, 2021 RNA sequencing (RNA-Seq) experiments focused on gene expression involve removal of ribosomal RNA (rRNA) because it is the major RNA constituent of cells.
Calla L Telzrow +7 more
doaj +1 more source
Intracerebral Hemorrhage and Ischemic Stroke of Different Etiologies Have Distinct Alternatively Spliced mRNA Profiles in the Blood: a Pilot RNA-seq Study. [PDF]
, 2015 Whole transcriptome studies have used 3'-biased expression microarrays to study genes regulated in the blood of stroke patients. However, alternatively spliced messenger RNA isoforms have not been investigated for ischemic stroke or intracerebral ...
Ander, Bradley P +8 more
core +2 more sources
Biological Procedures Online, 2023 Background RNA sequencing has become the gold standard for transcriptome analysis but has an inherent limitation of challenging quantification of low-abundant transcripts.
Celine Everaert +6 more
doaj +1 more source
Native RNA or cDNA Sequencing for Transcriptomic Analysis: A Case Study on Saccharomyces cerevisiae
Frontiers in Bioengineering and Biotechnology, 2022 Direct sequencing of single molecules through nanopores allows for accurate quantification and full-length characterization of native RNA or complementary DNA (cDNA) without amplification.
Thidathip Wongsurawat +3 more
doaj +1 more source