HSV ICP27 hijacks host splicing factor SRSF3 to regulate pre-mRNA splicing and export for viral gene expression and immune evasion. [PDF]
Tang S +4 more
europepmc +1 more source
RNA variation as the driver of genomic efficiency and phenotypic complexity. [PDF]
Jiang Z +7 more
europepmc +1 more source
A cost‐effective DNA extraction protocol for long‐read sequencing in non‐model plants
Abstract Premise Third‐generation sequencing has revolutionized genomics, enabling in‐depth analysis of genome sequence, structure, and epigenetic features. Yet, extracting high‐quality DNA for long‐read sequencing remains a bottleneck—particularly in non‐model plants, such as mature trees growing in natural environments, which often contain abundant ...
Sofia Gaischuk +6 more
wiley +1 more source
Herpesvirus-encoded lncRNA targets host splicing by interacting with splicing factors. [PDF]
Hong Y +12 more
europepmc +1 more source
This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang +9 more
wiley +1 more source
Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer. [PDF]
Wagner V +25 more
europepmc +1 more source
Exon inclusion signatures enable accurate estimation of splicing factor activity. [PDF]
Anglada-Girotto M +6 more
europepmc +1 more source
Advantages and Challenges of G‑Quadruplexes in Regulating Alternative Splicing. [PDF]
Huang H, Zhou X.
europepmc +1 more source
Binding of RbFox proteins at weak 5'splice site of A2 induces its alternative splicing in non-muscle myosin heavy-chain IIA mRNA. [PDF]
Mallick D, Pal N, Dutta S, Jana SS.
europepmc +1 more source
Shared splicing dysregulation in heart failure associated with dilated and ischaemic cardiomyopathy and spatial specificity across cardiac regions. [PDF]
Furtado M +10 more
europepmc +1 more source

