Results 261 to 270 of about 8,269,931 (302)

Comparative analysis of TP53 gene in Tupaia belangeri subspecies (Tupaia belangeri yaoshanensis vs. Tupaia belangeri chinensis) and identification of mutations in spontaneous tumor cases

Animal Models and Experimental Medicine, EarlyView.
This study provides the first evidence of natural TP53 variation between tree shrew subspecies and identifies somatic TP53 mutations in spontaneous tree shrew sarcomas. The high structural and functional conservation of tree shrew p53 with humans supports its utility as a relevant model for TP53‐related cancer research.
Yingying Cao, Haibo Tang, Liang Liang, Jing Leng, Weijian Huang   +4 more
wiley   +1 more source

RNA Splicing Dysregulation in Parkinson's Disease. [PDF]

Genes (Basel)
Bruno MG, Menichetti G, Valentino A, Javaid A, Belpinati F, Ruggiero A, Valenti MT, Paolone G, Cavaliere F, Trabetti E, Romanelli MG, Bombieri C.   +11 more
europepmc   +1 more source

Comprehensive and Combined Omics Analysis Reveals Immune-Infiltration-Associated Alternative Splicing and RBP Regulators Contributing to Ischemia-Reperfusion Injury in Liver Transplantation. [PDF]

Int J Genomics
Gui B, Huang H.
europepmc   +1 more source

LncRNA-driven alternative splicing landscapes associate with survival outcomes in ovarian cancer. [PDF]

Noncoding RNA Res
Cao Y, Zhao J, He S, Wu Q, Wang Y, Wu J, Liu J, Xie Y, Song X.   +8 more
europepmc   +1 more source

Circular RNAs Associated with Human Cytomegalovirus Infection. [PDF]

Molecules
Pagtalunan CJ, Zhang I, Liu F.
europepmc   +1 more source

Assembly of exon junction complexes on spliceosomes begins before spliceosome activation. [PDF]

Nucleic Acids Res
Abshire ET, Maquat LE.
europepmc   +1 more source

Nuclearly Encoded Splicing Factors Implicated in RNA Splicing in Higher Plant Organelles [PDF]

Molecular Plant, 2010
Plant organelles arose from two independent endosymbiosis events. Throughout evolutionary history, tight control of chloroplasts and mitochondria has been gained by the nucleus, which regulates most steps of organelle genome expression and metabolism.
Ian Small, Claire Lurin, Andéol Falcon de Longevialle   +2 more
exaly   +3 more sources

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The role of RNA splicing factor PTBP1 in neuronal development

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2023
Alternative pre-mRNA splicing, which produces various mRNA isoforms with distinct structures and functions from a single gene, is regulated by specific RNA-binding proteins and is an essential method for regulating gene expression in mammals. Recent studies have shown that abnormal change during neuronal development triggered by splicing mis-regulation
Hui-Lin, Liu, Xiu-Min, Lu, Hai-Yan, Wang, Kai-Bin, Hu, Qing-Yun, Wu, Ping, Liao, Sen, Li, Zai-Yun, Long, Yong-Tang, Wang   +8 more
openaire   +2 more sources

Mutations of RNA splicing factors in hematological malignancies

Cancer Letters, 2017
Systematic large-scale cancer genomic studies have produced numerous significant findings. These studies have not only revealed new cancer-promoting genes, but they also have identified cancer-promoting functions of previously known "housekeeping" genes.
Girish C. Shukla, Jagjit Singh
openaire   +2 more sources