Rna splicing factors - Open Access .click

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Cell-type-specific splicing factors and the regulation of alternative RNA splicing.

The New biologist, 1991
A very wide variety of biological processes are regulated by alternative splicing. By this means, a gene can be transcribed in several different tissues but in each tissue the RNA transcript is spliced in a particular way to produce a different mRNA and hence a different protein.
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A dual DNA/RNA-binding factor regulates co-transcriptional splicing through target RNA interaction and modulates splicing factor dynamics

Summary How RNA splicing events are targeted to the correct genomic locations in specific cellular contexts to generate context-specific transcript diversity and prevent deleterious cryptic splicing remains very poorly understood.
Mukulika Ray +17 more
openaire +2 more sources

RNA splicing dysregulation and the hallmarks of cancer

Nature Reviews Cancer, 2023
Robert K. Bradley, Olga Anczuków
exaly

Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

Cell, 2021
Benjamin D. Greenbaum, Jedd D. Wolchok, Harshal Shah +2 more
exaly

Dysregulation and therapeutic targeting of RNA splicing in cancer

Nature Cancer, 2022
Omar Abdel-Wahab, Robert Stanley
exaly

Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia

Cancer Cell, 2023
Emily Creger, Carine Bossard
exaly

Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer

Cancer Cell, 2020
Luisa F Escobar-Hoyos +2 more
exaly

Mechanistic insights into precursor messenger RNA splicing by the spliceosome

Nature Reviews Molecular Cell Biology, 2017
Yigong Shi
exaly