Results 21 to 30 of about 1,640,958 (330)

RNA structure

open access: yesCurrent Opinion in Structural Biology, 1998
New information concerning RNA structure is accumulating at an ever increasing rate-from short helices with mismatched bases of 5S rRNA and complex RNA aptamers. The importance of recurring structural motifs, ion binding, and the kinetics and energetics of folding in RNA structure and function is now being recognized and addressed.
Conn, Graeme L., Draper, David E.
openaire   +3 more sources

Molecular Characterization of Reduced Susceptibility to Biocides in Clinical Isolates of Acinetobacter baumannii

open access: yesFrontiers in Microbiology, 2017
Active efflux is regarded as a common mechanism for antibiotic and biocide resistance. However, the role of many drug efflux pumps in biocide resistance in Acinetobacter baumannii remains unknown. Using biocide-resistant A.
Fei Lin   +8 more
doaj   +1 more source

RNAlign2D: a rapid method for combined RNA structure and sequence-based alignment using a pseudo-amino acid substitution matrix

open access: yesBMC Bioinformatics, 2021
Background The functions of RNA molecules are mainly determined by their secondary structures. These functions can also be predicted using bioinformatic tools that enable the alignment of multiple RNAs to determine functional domains and/or classify RNA ...
Tomasz Woźniak   +3 more
doaj   +1 more source

Structural 3D Domain Reconstruction of the RNA Genome from Viruses with Secondary Structure Models

open access: yesViruses, 2021
Three-dimensional RNA domain reconstruction is important for the assembly, disassembly and delivery functionalities of a packed proteinaceus capsid. However, to date, the self-association of RNA molecules is still an open problem. Recent chemical probing
Simón Poblete, Horacio V. Guzman
doaj   +1 more source

Deep Learning in RNA Structure Studies

open access: yesFrontiers in Molecular Biosciences, 2022
Deep learning, or artificial neural networks, is a type of machine learning algorithm that can decipher underlying relationships from large volumes of data and has been successfully applied to solve structural biology questions, such as RNA structure ...
Haopeng Yu, Yiman Qi, Yiliang Ding
doaj   +1 more source

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

open access: yes, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B.   +4 more
core   +1 more source

SSRTool: A web tool for evaluating RNA secondary structure predictions based on species-specific functional interpretability

open access: yesComputational and Structural Biotechnology Journal, 2022
RNA secondary structures can carry out essential cellular functions alone or interact with one another to form the hierarchical tertiary structures.
Tzu-Hsien Yang   +3 more
doaj   +1 more source

A 212-nt long RNA structure in the Tobacco necrosis virus-D RNA genome is resistant to Xrn degradation [PDF]

open access: yes, 2019
Plus-strand RNA viruses can accumulate viral RNA degradation products during infections. Some of these decay intermediates are generated by the cytosolic 5′-to-3′ exoribonuclease Xrn1 (mammals and yeast) or Xrn4 (plants) and are formed when the enzyme ...
Chaminda, Gunawardene D.   +2 more
core   +1 more source

It's a loop world – single strands in RNA as structural and functional elements

open access: yesBiomolecular Concepts, 2011
Unpaired regions in RNA molecules – loops – are centrally involved in defining the characteristic three-dimensional (3D) architecture of RNAs and are of high interest in RNA engineering and design.
Schudoma Christian
doaj   +1 more source

RNApolis: Computational Platform for RNA Structure Analysis

open access: yesFoundations of Computing and Decision Sciences, 2019
In the 1970s, computer scientists began to engage in research in the field of structural biology. The first structural databases, as well as models and methods supporting the analysis of biomolecule structures, started to be created.
Szachniuk Marta
doaj   +1 more source

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