Expansion of the global RNA virome reveals diverse clades of bacteriophages
High-throughput RNA sequencing offers broad opportunities to explore the Earth RNA virome. Mining 5,150 diverse metatranscriptomes uncovered >2.5 million RNA virus contigs. Analysis of >330,000 RNA-dependent RNA polymerases (RdRPs) shows that this expansion corresponds to a 5-fold increase of the known RNA virus diversity.
Uri Neri +109 more
semanticscholar +10 more sources
Viromics Reveal a Number of Novel RNA Viruses in Swedish Mosquitoes [PDF]
Metagenomic studies of mosquitoes have revealed that their virome is far more diverse and includes many more viruses than just the pathogenic arboviruses vectored by mosquitoes.
Pontus Öhlund +4 more
doaj +6 more sources
Virome profiling of Culex tarsalis through small RNA-seq: A challenge of suboptimal samples. [PDF]
Viral infections in mosquitoes trigger the RNA interference (RNAi) pathway, a key antiviral defense mechanism that generates virus-derived small RNAs (vsRNAs).
Jaime Manzano-Alvarez +4 more
doaj +2 more sources
An efficient metatranscriptomic approach for capturing RNA virome and its application to SARS-CoV-2. [PDF]
Meng Y, Xiao L, Chen W, Zhao F, Zhao X.
europepmc +2 more sources
A Comprehensive Review: Molecular Diagnostics and Multi-Omics Approaches to Understanding Bovine Respiratory Disease [PDF]
Bovine respiratory disease (BRD) is a multifactorial syndrome and a leading cause of morbidity and economic loss in global cattle production. Next-generation sequencing (NGS) platforms, including Illumina and Oxford Nanopore Technologies (ONT), have ...
Stephanie O’Donoghue +3 more
doaj +2 more sources
Environmental viromes reveal global virosphere of deep-sea sediment RNA viruses
Introduction: Viruses are the most abundant and diverse life forms on the earth. Both DNA viruses and RNA viruses play important roles in marine ecosystems via regulating biogeochemical cycles.
Xinyi Zhang +4 more
doaj +3 more sources
Viromes in marine ecosystems reveal remarkable invertebrate RNA virus diversity [PDF]
AbstractOcean viromes remain poorly understood and little is known about the ecological factors driving aquatic RNA virus evolution. In this study, we used a meta-transcriptomic approach to characterize the viromes of 58 marine invertebrate species across three seas.
Yu-Yi Zhang +3 more
openaire +2 more sources
Cryptic and abundant marine viruses at the evolutionary origins of Earth’s RNA virome
Whereas DNA viruses are known to be abundant, diverse, and commonly key ecosystem players, RNA viruses are insufficiently studied outside disease settings. In this study, we analyzed ≈28 terabases of Global Ocean RNA sequences to expand Earth’s RNA virus
A. Zayed +56 more
semanticscholar +1 more source
The Mediterranean fruit fly (medfly), Ceratitis capitata, is an agricultural pest of a wide range of fruits. The advent of high-throughput sequencing has boosted the discovery of RNA viruses infecting insects.
Luis Hernández-Pelegrín +6 more
doaj +1 more source
Association of virome dynamics with mosquito species and environmental factors
Background The pathogenic viruses transmitted by mosquitoes cause a variety of animal and human diseases and public health concerns. Virome surveillance is important for the discovery, and control of mosquito-borne pathogenic viruses, as well as early ...
Qing Liu +12 more
doaj +1 more source

