Results 251 to 260 of about 323,847 (388)

MIG-21 interacts with Wnt and Netrin signaling in gonad migration in C. elegans. [PDF]

PLoS Genet
Li X, Gordon KL.
europepmc   +1 more source

P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders

Medicine Bulletin, EarlyView.
ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley   +1 more source

RNAi technology and its use in studying the function of nuclear receptors and coregulators [PDF]

, 2003
Haijun Zhou, Sophia Y. Tsai, Ming‐Jer Tsai   +2 more
openalex   +1 more source

SIFamide-dependent synaptic plasticity in male-specific GABAergic neurons underlies experience-modulated mating behaviors. [PDF]

iScience
Zhang T, Miao H, Song Y, Wu Z, Kim WJ.
europepmc   +1 more source

Rad51 at the Crossroads: Bridging DNA Repair, Tumorigenesis, and Immune Regulation

Med Research, EarlyView.
Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy); (2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 inhibitors, CRISPR/Cas9); and (4) combination approaches (immunotherapy). The figure is created with BioRender.com.
Zhendong Qin, Mingjun Lu, Jingwei Guo, Chenyang Wang, Teng Ma   +4 more
wiley   +1 more source

SiRNF8 Delivered by DNA Framework Nucleic Acid Effectively Sensitizes Chemotherapy in Colon Cancer

International Journal of Nanomedicine
Zhao Guo,1,* Haoyun Song,1,* Yingxia Tian,2,* Jie Xu,3 Guokun Zhang,1 Yanan Guo,1 Rong Shen,1 Degui Wang1 1Department of Anatomy and Histology, Lanzhou University School of Basic Medical Sciences, Lanzhou, 730000, People’s Republic of China ...
Guo Z, Song H, Tian Y, Xu J, Zhang G, Guo Y, Shen R, Wang D   +7 more
doaj  

RNAi and the shape of things to come. [PDF]

, 2003
Jonathan B Weitzman
openalex   +1 more source

Neuronal detection triggers systemic digestive shutdown in response to adverse food sources in <i>Caenorhabditis elegans</i>. [PDF]

Elife
Liu Y, Tian G, Wang Z, Zheng J, Liu H, Zhu S, Shan Z, Qi B.   +7 more
europepmc   +1 more source

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Nature, 2011
J. Zuber, Junwei Shi, E. Wang, Amy R. Rappaport, H. Herrmann, E. Sison, D. Magoon, J. Qi, Katharina Blatt, M. Wunderlich, Meredith J. Taylor, C. Johns, A. Chicas, J. Mulloy, S. Kogan, P. Brown, P. Valent, J. Bradner, S. Lowe, C. Vakoc   +19 more
semanticscholar   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source