Results 11 to 20 of about 1,043,746 (362)
On an RNA-Membrane Protogenome. [PDF]
Life (Basel)Selected ribonucleotide sequences bind well to zwitterionic phospholipid bilayer membranes, though randomized RNAs do not. There are no evident repeated sequences in selected membrane binding RNAs. This implies small and varied motifs responsible for membrane affinity. Such subsequences have been partially defined. Bound RNAs require divalents like Mg2+
Yarus M.
europepmc +2 more sources
Small RNA Profile in Moso Bamboo Root and Leaf Obtained by High Definition Adapters [PDF]
, 2014 Moso bamboo (Phyllostachy heterocycla cv. pubescens L.) is an economically important fast-growing tree. In order to gain better understanding of gene expression regulation in this important species we used next generation sequencing to profile small RNAs
A Kozomara +57 more
core +11 more sources
Investigation of molecular regulation mechanism under the pathophysiology of subarachnoid hemorrhage
Open Life Sciences, 2021 This study aimed to investigate the molecular mechanism under the pathophysiology of subarachnoid hemorrhage (SAH) and identify the potential biomarkers for predicting the risk of SAH.
Weng Yifei
doaj +1 more source
mSystems, 2022 Staphylococcus aureus is a major human and animal pathogen, colonizing diverse ecological niches within its hosts. Predicting whether an isolate will infect a specific host and its subsequent clinical fate remains unknown.
Mohamed Sassi +8 more
doaj +1 more source
Thermodynamics of RNA–RNA binding [PDF]
Bioinformatics, 2006 Abstract Background: Reliable prediction of RNA–RNA binding energies is crucial, e.g. for the understanding on RNAi, microRNA–mRNA binding and antisense interactions. The thermodynamics of such RNA–RNA interactions can be understood as the sum of two energy contributions: (1) the energy necessary to ‘open’ the binding site and (2) the ...
Stephan H. Bernhart +5 more
openaire +2 more sources
METTL16 in human diseases: What should we do next?
Open Medicine, 2023 METTL16 is a class-I methyltransferase that is responsible for depositing a vertebrate-conserved S-adenosylmethionine site. Since 2017, there has been a growing body of research focused on METTL16, particularly in the field of structural studies. However,
Zhang Hui +4 more
doaj +1 more source
Toxins, 2021 The authors wish to make the following corrections to their paper [...]
Sylvie Nonin-Lecomte +3 more
doaj +1 more source
RNA-Catalyzed RNA Ligation on an External RNA Template [PDF]
Chemistry & Biology, 2002 Variants of the hc ligase ribozyme, which catalyzes ligation of the 3' end of an RNA substrate to the 5' end of the ribozyme, were utilized to evolve a ribozyme that catalyzes ligation reactions on an external RNA template. The evolved ribozyme catalyzes the joining of an oligonucleotide 3'-hydroxyl to the 5'-triphosphate of an RNA hairpin molecule ...
Gerald F. Joyce, Kathleen E. McGinness
openaire +3 more sources
Nanocircular RNAs for RNA interference [PDF]
Nucleic Acids Symposium Series, 2008 We designed and synthesized dumbbell-shaped nanocircular RNAs for RNA interference applications, which consist of a stem and two loops(1). RNA dumbbells are specifically recognized and cleaved by the human Dicer enzyme, and are thus transformed into double-stranded RNA in cells, although this RNA is resistant to degradation in serum.
Naoko Abe +4 more
openaire +3 more sources
Galleria mellonella as a Suitable Model of Bacterial Infection: Past, Present and Future
Frontiers in Cellular and Infection Microbiology, 2021 The increasing interest for Galleria mellonella larvae as an infection model is evidenced by the number of papers reporting its use, which increases exponentially since the early 2010s.
Guillaume Ménard +3 more
doaj +1 more source