Results 21 to 30 of about 495,103 (267)
Advances in the chemical synthesis of RNA have opened new possibilities to address current questions in RNA biology. Access to site-specifically modified oligoribonucleotides is often a pre-requisite for RNA chemical-biology projects. Driven by the enormous research efforts for development of oligonucleotide therapeutics, a wide range of ...
Rothlisberger, Pascal +2 more
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RNA-Catalyzed RNA Ligation on an External RNA Template [PDF]
Variants of the hc ligase ribozyme, which catalyzes ligation of the 3' end of an RNA substrate to the 5' end of the ribozyme, were utilized to evolve a ribozyme that catalyzes ligation reactions on an external RNA template. The evolved ribozyme catalyzes the joining of an oligonucleotide 3'-hydroxyl to the 5'-triphosphate of an RNA hairpin molecule ...
McGinness, Kathleen E, Joyce, Gerald F
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RNA as Multitude/RNA as One [PDF]
In the configurations formed by RNA and its ions there are structural possibilities not yet realized; some are hinted at in new work on the binding of an amino acid analog.
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Fast prediction of RNA-RNA interaction [PDF]
Abstract Background Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by establishing stable interactions with a target sequence. There is great demand for efficient computational methods to predict the specific interaction between an ncRNA and its ...
Salari, Raheleh +2 more
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Single-photon microscopy to study biomolecular condensates
Biomolecular condensates serve as membrane-less compartments within cells, concentrating proteins and nucleic acids to facilitate precise spatial and temporal orchestration of various biological processes.
Eleonora Perego +10 more
doaj +1 more source
Small regulatory RNAs (sRNAs) are key players in bacterial regulatory networks. Monitoring their expression inside living colonized or infected organisms is essential for identifying sRNA functions, but few studies have looked at sRNA expression during ...
Guillaume Ménard +5 more
doaj +1 more source
Topology of RNA-RNA Interaction Structures [PDF]
40 pages 15 ...
Jørgen E. Andersen +3 more
openaire +7 more sources
Small non-coding RNAs: Diagnostic and therapeutic news [PDF]
Non-coding RNAs represent a specific type of RNAs that are non translated into proteins. They participate in a number of different regulatory processes concerning the transcriptional and posttranscriptional level.
Kocić Gordana
doaj
The aim of the study was to characterize the antimicrobial activity of clinically-relevant biocides (chlorhexidine digluconate, benzalkonium chloride, PVP-iodine and triclosan) and to determine the sRNA expression profiles under biocide exposure in two ...
Loren Dejoies +4 more
doaj +1 more source
Yersinia ruckeri causes outbreaks of enteric redmouth disease in salmon aquaculture all over the world. The transient antibiotic tolerance exhibited by bacterial persisters is commonly thought to be responsible for outbreaks; however, the molecular ...
Iván L. Calderón +5 more
doaj +1 more source

