Results 21 to 30 of about 495,103 (267)

RNA Chemistry for RNA Biology

open access: yesCHIMIA, 2019
Advances in the chemical synthesis of RNA have opened new possibilities to address current questions in RNA biology. Access to site-specifically modified oligoribonucleotides is often a pre-requisite for RNA chemical-biology projects. Driven by the enormous research efforts for development of oligonucleotide therapeutics, a wide range of ...
Rothlisberger, Pascal   +2 more
openaire   +5 more sources

RNA-Catalyzed RNA Ligation on an External RNA Template [PDF]

open access: yesChemistry & Biology, 2002
Variants of the hc ligase ribozyme, which catalyzes ligation of the 3' end of an RNA substrate to the 5' end of the ribozyme, were utilized to evolve a ribozyme that catalyzes ligation reactions on an external RNA template. The evolved ribozyme catalyzes the joining of an oligonucleotide 3'-hydroxyl to the 5'-triphosphate of an RNA hairpin molecule ...
McGinness, Kathleen E, Joyce, Gerald F
openaire   +2 more sources

RNA as Multitude/RNA as One [PDF]

open access: yesChemistry & Biology, 2003
In the configurations formed by RNA and its ions there are structural possibilities not yet realized; some are hinted at in new work on the binding of an amino acid analog.
openaire   +2 more sources

Fast prediction of RNA-RNA interaction [PDF]

open access: yesAlgorithms for Molecular Biology, 2009
Abstract Background Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by establishing stable interactions with a target sequence. There is great demand for efficient computational methods to predict the specific interaction between an ncRNA and its ...
Salari, Raheleh   +2 more
openaire   +7 more sources

Single-photon microscopy to study biomolecular condensates

open access: yesNature Communications, 2023
Biomolecular condensates serve as membrane-less compartments within cells, concentrating proteins and nucleic acids to facilitate precise spatial and temporal orchestration of various biological processes.
Eleonora Perego   +10 more
doaj   +1 more source

Galleria mellonella Larvae as an Infection Model to Investigate sRNA-Mediated Pathogenesis in Staphylococcus aureus

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Small regulatory RNAs (sRNAs) are key players in bacterial regulatory networks. Monitoring their expression inside living colonized or infected organisms is essential for identifying sRNA functions, but few studies have looked at sRNA expression during ...
Guillaume Ménard   +5 more
doaj   +1 more source

Topology of RNA-RNA Interaction Structures [PDF]

open access: yesJournal of Computational Biology, 2012
40 pages 15 ...
Jørgen E. Andersen   +3 more
openaire   +7 more sources

Small non-coding RNAs: Diagnostic and therapeutic news [PDF]

open access: yesJournal of Medical Biochemistry, 2008
Non-coding RNAs represent a specific type of RNAs that are non translated into proteins. They participate in a number of different regulatory processes concerning the transcriptional and posttranscriptional level.
Kocić Gordana
doaj  

Distinct expression profiles of regulatory RNAs in the response to biocides in Staphylococcus aureus and Enterococcus faecium

open access: yesScientific Reports, 2021
The aim of the study was to characterize the antimicrobial activity of clinically-relevant biocides (chlorhexidine digluconate, benzalkonium chloride, PVP-iodine and triclosan) and to determine the sRNA expression profiles under biocide exposure in two ...
Loren Dejoies   +4 more
doaj   +1 more source

The RNA Chaperone Hfq Participates in Persistence to Multiple Antibiotics in the Fish Pathogen Yersinia ruckeri

open access: yesMicroorganisms, 2021
Yersinia ruckeri causes outbreaks of enteric redmouth disease in salmon aquaculture all over the world. The transient antibiotic tolerance exhibited by bacterial persisters is commonly thought to be responsible for outbreaks; however, the molecular ...
Iván L. Calderón   +5 more
doaj   +1 more source

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