Results 31 to 40 of about 1,710,125 (310)

RNA Chemistry for RNA Biology

open access: yesCHIMIA, 2019
Advances in the chemical synthesis of RNA have opened new possibilities to address current questions in RNA biology. Access to site-specifically modified oligoribonucleotides is often a pre-requisite for RNA chemical-biology projects. Driven by the enormous research efforts for development of oligonucleotide therapeutics, a wide range of ...
Rothlisberger, Pascal   +2 more
openaire   +5 more sources

Topology of RNA-RNA Interaction Structures [PDF]

open access: yesJournal of Computational Biology, 2012
40 pages 15 ...
Jørgen E. Andersen   +3 more
openaire   +6 more sources

Cooperativity and Interdependency between RNA Structure and RNA–RNA Interactions [PDF]

open access: yesNon-Coding RNA, 2021
Complex RNA–RNA interactions are increasingly known to play key roles in numerous biological processes from gene expression control to ribonucleoprotein granule formation. By contrast, the nature of these interactions and characteristics of their interfaces, especially those that involve partially or wholly structured RNAs, remain elusive.
Ilias Skeparnias, Jinwei Zhang
openaire   +3 more sources

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses.

open access: yesGenes & Development, 2011
Large intergenic noncoding RNAs (lincRNAs) are emerging as key regulators of diverse cellular processes. Determining the function of individual lincRNAs remains a challenge.
M. Cabili   +6 more
semanticscholar   +1 more source

Fast prediction of RNA-RNA interaction [PDF]

open access: yesAlgorithms for Molecular Biology, 2009
Abstract Background Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by establishing stable interactions with a target sequence. There is great demand for efficient computational methods to predict the specific interaction between an ncRNA and its ...
Salari, Raheleh   +2 more
openaire   +6 more sources

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

open access: yesNature, 2009
There is growing recognition that mammalian cells produce many thousands of large intergenic transcripts. However, the functional significance of these transcripts has been particularly controversial.
M. Guttman   +19 more
semanticscholar   +1 more source

Distinct expression profiles of regulatory RNAs in the response to biocides in Staphylococcus aureus and Enterococcus faecium

open access: yesScientific Reports, 2021
The aim of the study was to characterize the antimicrobial activity of clinically-relevant biocides (chlorhexidine digluconate, benzalkonium chloride, PVP-iodine and triclosan) and to determine the sRNA expression profiles under biocide exposure in two ...
Loren Dejoies   +4 more
doaj   +1 more source

The RNA Chaperone Hfq Participates in Persistence to Multiple Antibiotics in the Fish Pathogen Yersinia ruckeri

open access: yesMicroorganisms, 2021
Yersinia ruckeri causes outbreaks of enteric redmouth disease in salmon aquaculture all over the world. The transient antibiotic tolerance exhibited by bacterial persisters is commonly thought to be responsible for outbreaks; however, the molecular ...
Iván L. Calderón   +5 more
doaj   +1 more source

Stress response and virulence factors in bacterial pathogens relevant for Chilean aquaculture: current status and outlook of our knowledge

open access: yesBiological Research, 2022
The study of the stress responses in bacteria has given us a wealth of information regarding the mechanisms employed by these bacteria in aggressive or even non-optimal living conditions.
Derie E. Fuentes   +2 more
doaj   +1 more source

RNA as Multitude/RNA as One [PDF]

open access: yesChemistry & Biology, 2003
In the configurations formed by RNA and its ions there are structural possibilities not yet realized; some are hinted at in new work on the binding of an amino acid analog.
openaire   +2 more sources

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