Results 51 to 60 of about 571,579 (318)

Populus Short RNAs

open access: yes, 2011
As a model species, Populus offers opportunities to study processes unique to woody, perennial species, such as seasonal senescence, dormancy and wood production.
Nathaniel Robert Street   +1 more
core   +1 more source

An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]

open access: yes, 2013
Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Darren M. Gowers (485354)   +29 more
core   +1 more source

Employing single-cell RNA sequencing coupled with an array of bioinformatics approaches to ascertain the shared genetic characteristics between osteoporosis and obesity

open access: yesBone & Joint Research
Aims: This study examined the relationship between obesity (OB) and osteoporosis (OP), aiming to identify shared genetic markers and molecular mechanisms to facilitate the development of therapies that target both conditions simultaneously.
Dingzhuo Liu   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Long Non-coding RNAs in Human Disease

open access: yes, 2016
This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing.No Full ...
Morris, Kevin V
core   +1 more source

Next generation sequencing for studying viruses and RNA silencing-based antiviral defense in crop plants [PDF]

open access: yes, 2014
The main objectives of this work have been to use next generation sequencing (NGS) and develop bioinformatics tools for plant virus diagnostics and genome reconstruction as well as for investigation of RNA silencing-based antiviral defense.
Seguin, Jonathan
core   +1 more source

Comparisons of miRNA profiles of exosomes derived from human iPSCs, ADSCs, and BMSCs and effects on chondrocyte function

open access: yesBone & Joint Research
Aims: This study aimed to identify and compare the microRNA (miRNA) profiles of exosomes derived from human induced pluripotent stem cells (iPSCs), bone marrow mesenchymal stem cells (BMSCs), and adipose tissue-derived stem cells (ADSCs) (hiPSC-Exos ...
Ling-Hua Chang   +11 more
doaj   +1 more source

Non-Coding RNAs and SARS-Related Coronaviruses

open access: yesViruses, 2020
The emergence of SARS-CoV-2 in 2019 has caused a major health and economic crisis around the globe. Gaining knowledge about its attributes and interactions with human host cells is crucial.
Hanna Henzinger   +3 more
doaj   +1 more source

An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA [PDF]

open access: yesNature, 2009
Constitutive expression of telomerase in human cells prevents the onset of senescence and crisis by maintaining telomere homeostasis. However, accumulating evidence suggests that the human telomerase reverse transcriptase catalytic subunit (TERT) contributes to cell physiology independently of its ability to elongate telomeres.
Maida, Yoshiko   +9 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy