Results 41 to 50 of about 1,043,746 (362)
Scientific Reports, 2021 The aim of the study was to characterize the antimicrobial activity of clinically-relevant biocides (chlorhexidine digluconate, benzalkonium chloride, PVP-iodine and triclosan) and to determine the sRNA expression profiles under biocide exposure in two ...
Loren Dejoies +4 more
doaj +1 more source
Traffic into silence: endomembranes and post-transcriptional RNA silencing. [PDF]
, 2014 microRNAs (miRNAs) and small interfering RNAs (siRNAs) are small RNAs that repress gene expression at the post-transcriptional level in plants and animals. Small RNAs guide Argonaute-containing RNA-induced silencing complexes to target RNAs in a sequence-
Chen, Xuemei +2 more
core +3 more sources
Involvement of Long Non-Coding RNAs (lncRNAs) in Tumor Angiogenesis
Non-Coding RNA, 2020 Long non-coding RNAs (lncRNAs) are defined as non-protein coding transcripts with a minimal length of 200 nucleotides. They are involved in various biological processes such as cell differentiation, apoptosis, as well as in pathophysiological processes ...
Julia Teppan +5 more
doaj +1 more source
Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer
Non-Coding RNA, 2020 Hypoxia is dangerous for oxygen-dependent cells, therefore, physiological adaption to cellular hypoxic conditions is essential. The transcription factor hypoxia-inducible factor (HIF) is the main regulator of hypoxic metabolic adaption reducing oxygen ...
Dominik A. Barth +5 more
doaj +1 more source
A small RNA response at DNA ends in Drosophila [PDF]
, 2012 Small RNAs have been implicated in numerous cellular processes, including effects on chromatin structure and the repression of transposons. We describe the generation of a small RNA response at DNA ends in Drosophila that is analogous to the recently ...
Böttcher, Romy +2 more
core +1 more source
Unraveling RNA by Mechanical Unzipping [PDF]
arXiv, 2023 We review the basic concepts and tools for mechanically unzipping RNA hairpins using force spectroscopy. By pulling apart the ends of an RNA molecule using optical tweezers, it is possible to measure the folding free energy at varying experimental conditions.
arxiv
Small non-coding RNAs: Diagnostic and therapeutic news [PDF]
Journal of Medical Biochemistry, 2008 Non-coding RNAs represent a specific type of RNAs that are non translated into proteins. They participate in a number of different regulatory processes concerning the transcriptional and posttranscriptional level.
Kocić Gordana
doaj
Identification of RNAs Engaged in Direct RNA-RNA Interaction with a Long Non-Coding RNA
Journal of Visualized Experiments, 2021 The growing role attributed nowadays to long non-coding RNAs (lncRNA) in physiology and pathophysiology makes it crucial to characterize their interactome by identifying their molecular partners, DNA, proteins and/or RNAs. The latter can interact with lncRNA through networks involving proteins, but they can also be engaged in direct RNA/RNA ...
Jacq, Audrey +6 more
openaire +4 more sources
Solid phase chemistry to covalently and reversibly capture thiolated RNA. [PDF]
, 2018 Here, we describe an approach to enrich newly transcribed RNAs from primary mouse neurons using 4-thiouridine (s4U) metabolic labeling and solid phase chemistry.
Canzio, Daniele +3 more
core +1 more source
RNA-RNA and RNA-protein interactions in coronavirus replication and transcription [PDF]
RNA Biology, 2011 Coronavirus (CoV) RNA synthesis includes the replication of the viral genome, and the transcription of sgRNAs by a discontinuous mechanism. Both processes are regulated by RNA sequences such as the 5' and 3' untranslated regions (UTRs), and the transcription regulating sequences (TRSs) of the leader (TRS-L) and those preceding each gene (TRS-Bs). These
Solá Gurpegui, Isabel +4 more
openaire +4 more sources