Results 41 to 50 of about 2,156,375 (387)

RNA helicases in RNA decay [PDF]

open access: yesBiochemical Society Transactions, 2018
RNA molecules have the tendency to fold into complex structures or to associate with complementary RNAs that exoribonucleases have difficulties processing or degrading. Therefore, degradosomes in bacteria and organelles as well as exosomes in eukaryotes have teamed-up with RNA helicases.
Khemici, Vanessa, Linder, Patrick
openaire   +3 more sources

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes. [PDF]

open access: yes, 2017
RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA composition of EVs is challenging due to their coisolation with contaminants, lack of knowledge of the mechanisms of RNA sorting into EVs, and limitations of ...
Lambowitz, Alan M   +6 more
core   +1 more source

Involvement of Long Non-Coding RNAs (lncRNAs) in Tumor Angiogenesis

open access: yesNon-Coding RNA, 2020
Long non-coding RNAs (lncRNAs) are defined as non-protein coding transcripts with a minimal length of 200 nucleotides. They are involved in various biological processes such as cell differentiation, apoptosis, as well as in pathophysiological processes ...
Julia Teppan   +5 more
doaj   +1 more source

Inter- and Intramolecular recombinations in the Cucumber Mosaic Virus genome related to adaptation to Alstroemeria [PDF]

open access: yes, 2002
In four distinct alstroemeria-infecting cucumber mosaic virus (CMV) isolates, additional sequences of various lengths were present in the 3' nontranslated regions of their RNAs 2 and 3, apparently the result of intra- and intermolecular recombination ...
Chen, Y.K., Goldbach, R.W., Prins, M.W.
core   +4 more sources

Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer

open access: yesNon-Coding RNA, 2020
Hypoxia is dangerous for oxygen-dependent cells, therefore, physiological adaption to cellular hypoxic conditions is essential. The transcription factor hypoxia-inducible factor (HIF) is the main regulator of hypoxic metabolic adaption reducing oxygen ...
Dominik A. Barth   +5 more
doaj   +1 more source

Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer's disease. [PDF]

open access: yes, 2019
Lithium (Li) is a medication long-used to treat bipolar disorder. It is currently under investigation for multiple nervous system disorders, including Alzheimer's disease (AD).
Balaraman, Yokesh   +7 more
core   +3 more sources

RNA tectonics: towards RNA design

open access: yesFolding and Design, 1996
Our understanding of the structural, folding and catalytic properties of RNA molecules has increased enormously in recent years. The discovery of catalytic RNA molecules by Sidney Altman and Tom Cech, the development of in vitro selection procedures, and the recent crystallizations of hammerhead ribozymes and of a large domain of an autocatalytic group
Westhof, Eric   +2 more
openaire   +2 more sources

Moving RNA moves RNA forward [PDF]

open access: yesScience China Life Sciences, 2013
Cell communication affects all aspects of cell structure and behavior, such as cell proliferation, differentiation, division, and coordination of various physiological functions. The moving RNA in plants and mammalian cells indicates that nucleic acid could be one of the various types of messengers for cell communication. The microvesicle is a critical
Peng, LiNa   +3 more
openaire   +2 more sources

Employing single-cell RNA sequencing coupled with an array of bioinformatics approaches to ascertain the shared genetic characteristics between osteoporosis and obesity

open access: yesBone & Joint Research
Aims: This study examined the relationship between obesity (OB) and osteoporosis (OP), aiming to identify shared genetic markers and molecular mechanisms to facilitate the development of therapies that target both conditions simultaneously.
Dingzhuo Liu   +5 more
doaj   +1 more source

Small non-coding RNAs: Diagnostic and therapeutic news [PDF]

open access: yesJournal of Medical Biochemistry, 2008
Non-coding RNAs represent a specific type of RNAs that are non translated into proteins. They participate in a number of different regulatory processes concerning the transcriptional and posttranscriptional level.
Kocić Gordana
doaj  

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