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Targeted therapeutic RNases (ImmunoRNases)
Expert Opinion on Biological Therapy, 2008Immunotoxins combining antibody specificity with bacterial or plant toxins are limited by their strong immunogenicity and non-specific toxicity. Ribonucleases of the RNase A protein superfamily provide a solution to address these issues because they show potent antineoplastic activity on cell internalization but do not show appreciable immunogenicity ...
Thomas, Schirrmann +4 more
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Molecular Biology Reports, 1996
Molecular investigations in mitochondria of higher plants have to take in account the complicated genomic structure of these organelles and their complex mode of gene expression. Recently tRNA processing activities and particularly RNase P-like activities have been described for mitochondria of mono- and dicot plants.
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Molecular investigations in mitochondria of higher plants have to take in account the complicated genomic structure of these organelles and their complex mode of gene expression. Recently tRNA processing activities and particularly RNase P-like activities have been described for mitochondria of mono- and dicot plants.
openaire +2 more sources
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
Science, 2023Danyel Lee +2 more
exaly
Expressing Self-Incompatibility RNases (S-RNases) in Transgenic Plants
2003B, Beecher, B A, McClure
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RNase E: at the interface of bacterial RNA processing and decay
Nature Reviews Microbiology, 2012George A Mackie
exaly
When all's zed and done: the structure and function of RNase Z in prokaryotes
Nature Reviews Microbiology, 2007Ines Li de la Sierra-Gallay +1 more
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