Results 151 to 160 of about 290,253 (274)

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Expression of Moloney Murine Leukemia Virus RNase H Rescues the Growth Defect of an Escherichia coli Mutant

, 2001
Andrew G. Campbell
openalex   +1 more source

A Novel Thioredoxin h Is Secreted in Nicotiana alata and Reduces S-RNase in Vitro [PDF]

, 2005
Javier Andrés Juárez‐Díaz, Bruce McClure, Sonia Vázquez‐Santana, Arturo Guevara‐García, Patricia León-Mejía, Judith Márquez‐Guzmán, Felipe Cruz‐García   +6 more
openalex   +1 more source

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

Advanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera, Lena Kühn, Lisa Jungbluth, Verian Bader, Laura J. Krause, David Kartte, Elias Adriaenssens, Sascha Martens, Jörg Tatzelt, Carsten Sachse, Konstanze F. Winklhofer   +10 more
wiley   +1 more source

Comparison of Second-Strand Transfer Requirements and RNase H Cleavages Catalyzed by Human Immunodeficiency Virus Type 1 Reverse Transcriptase (RT) and E478Q RT

, 2000
Christine Smith Snyder, Monica J. Roth
openalex   +2 more sources

Purification of Saccharomyces cerevisiae RNase H(70) and identification of the corresponding gene [PDF]

, 1999
Peter Frank, Christa Braunshofer-Reiter, Anneliese Karwan, Rudolf Grimm, Ulrike Wintersberger   +4 more
openalex   +1 more source

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration. [PDF]

Nucleic Acids Res, 2021
Jafar-Nejad P, Powers B, Soriano A, Zhao H, Norris DA, Matson J, DeBrosse-Serra B, Watson J, Narayanan P, Chun SJ, Mazur C, Kordasiewicz H, Swayze EE, Rigo F.   +13 more
europepmc   +1 more source

Madurahydroxylactone Derivatives as Dual Inhibitors of Human Immunodeficiency Virus Type 1 Integrase and RNase H

, 2007
Christophe Marchand, John A. Beutler, Antony Wamiru, Scott R. Budihas, Ute Möllmann, Lothar Heinisch, John W. Mellors, S F Le Grice, Yves Pommier   +8 more
openalex   +1 more source

RNase H Overproduction Corrects a Defect at the Level of Transcription Elongation during rRNA Synthesis in the Absence of DNA Topoisomerase I in Escherichia coli [PDF]

, 2000
Chadi Hraiky, Marc-André Raymond, Marc Drolet   +2 more
openalex   +1 more source