The cloned RNA polymerase II transcription factor IID selects RNA polymerase III to transcribe the human U6 gene in vitro [PDF]
Although the human U2 and U6 snRNA genes are transcribed by different RNA polymerases (i.e., RNA polymerases II and III, respectively), their promoters are very similar in structure.
Hernandez, N.+3 more
core +1 more source
MicroRNAs (miRNAs) are non-coding RNAs, which, as members of the RNA interference pathway, play a pivotal role in antiviral infection. Almost 80% of plant viruses are transmitted by insect vectors; however, little is known about the interaction of the ...
Haitao Wang+5 more
doaj +1 more source
Evolutionary conundrum of RNase P: from a catalytic RNA form to a protein only enzyme form [PDF]
RNaza P je esencijalna endonukleaza koja katalizira procesiranje 5'-vodećeg slijeda pre-tRNA. Postoje dva tipa RNaze P: RNA-ovisni enzim tj ribonukleoprotein te isključivo proteinska RNaza P (PRORP).
Radman, Katarina
core
Silencing disease genes in the laboratory and the clinic
Synthetic nucleic acids are commonly used laboratory tools for modulating gene expression and have the potential to be widely used in the clinic. Progress towards nucleic acid drugs, however, has been slow and many challenges remain to be overcome before
Corey, David R., Watts, Jonathan K.
core +1 more source
A complex pathway for 3 ' processing of the yeast U3 snoRNA [PDF]
Mature U3 snoRNA in yeast is generated from the 3′-extended precursors by endonucleolytic cleavage followed by exonucleolytic trimming. These precursors terminate in poly(U) tracts and are normally stabilised by binding of the yeast La homologue, Lhp1p ...
Allmang, C+4 more
core +2 more sources
RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response [PDF]
PURPOSE: The aim of this study was to investigate whether expression of particular drug resistance genes in primary operable breast cancer correlates with response to first-line chemotherapy in advanced disease.
Burger, H. (Herman)+7 more
core +1 more source
RNAcentral: A vision for an international database of RNA sequences [PDF]
During the last decade there has been a great increase in the number of noncoding RNA genes identified, including new classes such as microRNAs and piRNAs.
Agrawal, Shipra+29 more
core +4 more sources
The parasite Trichomonas vaginalis expresses thousands of pseudogenes and long non-coding RNAs independently from functional neighbouring genes [PDF]
BACKGROUND: The human pathogen Trichomonas vaginalis is a parabasalian flagellate that is estimated to infect 3% of the world’s population annually.
Christian Woehle+5 more
core +1 more source
RNase MRP is a ribonucleoprotein endoribonuclease that has been shown to cleave mitochondrial primer RNA sequences from a variety of sources. Most of the RNase MRP activity is found in the nucleus where it plays a role in the processing of 5.8S rRNA.
M. Schmitt, David A. Clayton
semanticscholar +1 more source
Modulation of Neurogenesis through the Promotion of Energy Production Activity Is behind the Antidepressant-Like Effect of Colonial Green Alga, Botryococcus braunii [PDF]
Algae have been recognized as important resources providing functional components due to their capacity to exert beneficial effects on health. Therefore, there is increasing interest in investigating the biological activity of algae.
Demura Mikihide+6 more
core +1 more source