Archaeal/Eukaryal RNase P: subunits, functions and RNA diversification [PDF]
RNase P, a catalytic ribonucleoprotein (RNP), is best known for its role in precursor tRNA processing. Recent discoveries have revealed that eukaryal RNase P is also required for transcription and processing of select non-coding RNAs, thus enmeshing ...
Ablasser+115 more
core +2 more sources
Identification of RMP24 and RMP64, human ribonuclease MRP-specific protein components
Summary: Human RNase MRP is a ribonucleoprotein (RNP) enzyme that processes precursor rRNA (pre-rRNA) at ITS1 site 2 and may have additional activities. It is an endonuclease related to RNase P, which processes pre-tRNAs and pre-tRNA-like substrates.
Rui Che+5 more
doaj
Automated detection of ncRNAs in the draft genome sequence of a colonial tunicate: the carpet sea squirt Didemnum vexillum [PDF]
Statistics D. vexillum draft genome.
Adriaan A. Gittenberger+4 more
core +8 more sources
Processing of preribosomal RNA in Saccharomyces cerevisiae [PDF]
Most, if not all RNAs, are transcribed as precursors that require processing to gain functionality. Ribosomal RNAs (rRNA) from all organisms undergo both exo- and endonucleolytic processing.
Cruz, Jesús de la+2 more
core
Efficient termination of transcription by RNA polymerase I requires the 5 ' exonuclease Rat1 in yeast [PDF]
During transcription termination by RNA polymerase II on protein-coding genes, the nuclear 5′ exonuclease Rat1/Xrn2 degrades the nascent transcript downstream from the polyadenylation site and “torpedoes” the polymerase.
El Hage, Aziz+3 more
core +2 more sources
Nuclear RNA Surveillance in \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e: Trf4p-dependent Polyadenylation of Nascent Hypomethylated tRNA and an Aberrant Form of 5S rRNA [PDF]
1-Methyladenosine modification at position 58 of tRNA is catalyzed by a two-subunit methyltransferase composed of Trm6p and Trm61p in Saccharomyces cerevisiae.
Anderson, James T.+2 more
core +1 more source
Identification and Diagnostic Performance of a Small RNA within the PCA3 and BMCC1 Gene Locus That Potentially Targets mRNA [PDF]
Background: PCA3 is a long noncoding RNA (lncRNA) with unknown function, upregulated in prostate cancer. LncRNAs may be processed into smaller active species. We hypothesized this for PCA3.
Arndt Hartmann+18 more
core +1 more source
Efficient site-specific cleavage by RNase MRP requires interaction with two evolutionarily conserved mitochondrial RNA sequences. [PDF]
Jeffrey Bennett, David A. Clayton
openalex +1 more source
Reconstructing phylogeny from RNA secondary structure via simulated evolution
DNA sequences of genes encoding functional RNA molecules (e.g., ribosomal RNAs) are commonly used in phylogenetics (i.e. to infer evolutionary history).
Fischer, Will, Geard, Nicholas
core
Basic Domains Target Protein Subunits of the RNase MRP Complex to the Nucleolus Independently of Complex Association [PDF]
Hans van Eenennaam+4 more
openalex +1 more source