Rex1p Deficiency Leads to Accumulation of Precursor Initiator tRNA\u3csup\u3eMet\u3c/sup\u3e and Polyadenylation of Substrate RNAs in \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e [PDF]
A synthetic genetic array was used to identify lethal and slow-growth phenotypes produced when a mutation in TRM6, which encodes a tRNA modification enzyme subunit, was combined with the deletion of any non-essential gene in Saccharomyces cerevisiae.
Anderson, James T.+5 more
core +1 more source
Identification of a functional core in the RNA component of RNase MRP of budding yeasts [PDF]
X. Li
openalex +1 more source
Purification and Biophysical Study of RNase P Proteins 21 and 29 from Methanocaldococcus jannaschii [PDF]
RNase P is an endonuclease with a rare catalytic RNA core. The enzyme is a ribonucleoprotein (RNP) complex and is primarily responsible for cleaving the 5’ RNA leader sequence from precursor tRNA (ptRNA) molecules. The maturation of tRNA is necessary for
Smith, David
core
Functional characterization of the conserved amino acids in Pop1p, the largest common protein subunit of yeast RNases P and MRP [PDF]
Shaohua Xiao+5 more
openalex +1 more source
Ribozymes: the characteristics and properties of catalytic RNAs [PDF]
Ribozymes, or catalytic RNAs, were discovered a little more than 15 years ago. They are found in the organelles of plants and lower eukaryotes, in amphibians, in prokaryotes, in bacteriophages, and in viroids and satellite viruses that infect plants.
Tanner, N. Kyle
core
RNase MRP and the RNA processing cascade in the eukaryotic ancestor [PDF]
Background Within eukaryotes there is a complex cascade of RNA-based macromolecules that process other RNA molecules, especially mRNA, tRNA and rRNA. A simple example is the RNase MRP processing of ribosomal RNA (rRNA) in ribosome biogenesis.
Collins, Lesley J.+3 more
core +1 more source
Cryo-EM Structure of RNase MRP, a 12-Component Catalytic Ribonucleoprotein Complex
A. S. Krasilnikov+6 more
semanticscholar +1 more source
Transcription and export of rnase mrp rna inxenopus laevisoocytes [PDF]
Sunjoo Jeong
openalex +1 more source
3D models of yeast RNase P/MRP proteins Rpp1p and Pop3p [PDF]
Mensur Dlakić
openalex +1 more source
Specific binding of a Pop6/Pop7 heterodimer to the P3 stem of the yeast RNase MRP and RNase P RNAs [PDF]
Anna Perederina+4 more
openalex +1 more source