Results 11 to 20 of about 195 (84)
A new role for proteins subunits of RNase P: stabilization of the telomerase holoenzyme
Microbial Cell, 2020 RNase P, an RNA-protein complex, is essential for processing tRNAs. Three of the ten protein subunits of Saccharomyces cerevisiae RNase P (and a related complex, RNase MRP) co-purify with yeast telomerase, another RNA-protein complex.
P. Daniela Garcia, Virginia A. Zakian
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Identification of Non-Coding RNAs in the Candida parapsilosis Species Group. [PDF]
PLoS ONE, 2016 The Candida CTG clade is a monophyletic group of fungal species that translates CTG as serine, and includes the pathogens Candida albicans and Candida parapsilosis. Research has typically focused on identifying protein-coding genes in these species. Here,
Paul D Donovan +3 more
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Whole-exome re-sequencing in a family quartet identifies POP1 mutations as the cause of a novel skeletal dysplasia. [PDF]
PLoS Genetics, 2011 Recent advances in DNA sequencing have enabled mapping of genes for monogenic traits in families with small pedigrees and even in unrelated cases. We report the identification of disease-causing mutations in a rare, severe, skeletal dysplasia, studying a
Evgeny A Glazov +7 more
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Experimental and Molecular Medicine, 2023 Hepatitis B protein x (HBx) has been reported to promote tumorigenesis in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), but the mechanism awaits further investigation.
Jian Yu +11 more
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ABC transportome inventory of human pathogenic yeast Candida glabrata: Phylogenetic and expression analysis. [PDF]
PLoS ONE, 2018 ATP-binding cassette (ABC) is one of the two major superfamilies of transporters present across the evolutionary scale. ABC superfamily members came to prominence due to their ability to extrude broad spectrum of substrates and to confer multi drug ...
Sonam Kumari +11 more
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Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery. [PDF]
PLoS ONE, 2011 Trypanosoma brucei and related pathogens transcribe most genes as polycistronic arrays that are subsequently processed into monocistronic mRNAs. Expression is frequently regulated post-transcriptionally by cis-acting elements in the untranslated regions (
Jan Mani +7 more
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Scientific Reports, 2017 Mutations in the RMRP-gene, encoding the lncRNA component of the RNase MRP complex, are the origin of cartilage-hair hypoplasia. Cartilage-hair hypoplasia is associated with severe dwarfism caused by impaired skeletal development.
Mandy M. F. Steinbusch +10 more
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A method for rapid similarity analysis of RNA secondary structures
BMC Bioinformatics, 2006 Background Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolutionary analysis.
Liu Na, Wang Tianming
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Malaria Journal, 2009 Background The ATP-binding cassette (ABC) superfamily is one of the largest evolutionarily conserved families of proteins. ABC proteins play key roles in cellular detoxification of endobiotics and xenobiotics.
González-Méndez Ricardo +3 more
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BMC Genomics, 2009 Background Schistosomes are trematode parasites of the phylum Platyhelminthes. They are considered the most important of the human helminth parasites in terms of morbidity and mortality.
Santana Clara +8 more
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