Unveiling the Role of circRNAs in Pyroptotic Signalling: From Molecular Crosstalk to Disease Modulation. [PDF]
J Cell Mol MedABSTRACT Pyroptosis is a gasdermins‐dependent programmed cell death (PCD) characterised by progressive cellular swelling and plasma membrane rupture (PMR). This process releases intracellular contents that amplify inflammatory cascades and immune activation, involving the pathogenesis of various disorders such as tumours, heart and vascular diseases ...
Jin T, Xu G, Zhou W, Shi Y, Wang H.
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Sequence analysis of RNase MRP RNA reveals its origination from eukaryotic RNase P RNA [PDF]
RNA, 2006 RNase MRP is a eukaryote-specific endoribonuclease that generates RNA primers for mitochondrial DNA replication and processes precursor rRNA. RNase P is a ubiquitous endoribonuclease that cleaves precursor tRNA transcripts to produce their mature 5′ termini. We found extensive sequence homology of catalytic domains and specificity domains between their
Yanglong Zhu +3 more
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Wnt activated β-catenin and YAP proteins enhance the expression of non-coding RNA component of RNase MRP in colon cancer cells. [PDF]
Oncotarget, 2015 Park J, Jeong S.
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Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing. [PDF]
Genes Dev, 2017 Goldfarb KC, Cech TR.
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The rRNA methyltransferase Bud23 shows functional interaction with components of the SSU processome and RNase MRP. [PDF]
RNA, 2013 Sardana R, White JP, Johnson AW.
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hPop4: a new protein subunit of the human RNase MRP and RNase P ribonucleoprotein complexes [PDF]
Nucleic Acids Research, 1999 RNase MRP is a ribonucleoprotein particle involved in the processing of pre-rRNA. The RNase MRP particle is structurally highly related to the RNase P particle, which is involved in pre-tRNA processing. Their RNA components fold into a similar secondary structure and they share several protein subunits.
Hans van Eenennaam
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Interactions of a Pop5/Rpp1 heterodimer with the catalytic domain of RNase MRP. [PDF]
RNA, 2011 Perederina A +5 more
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RNase MRP and the RNA processing cascade in the eukaryotic ancestor. [PDF]
BMC Evol Biol, 2007 Woodhams MD +3 more
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RNase MRP RNA and RNase P activity in plants are associated with a Pop1p containing complex. [PDF]
Nucleic Acids Res, 2012 Krehan M +4 more
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RNase MRP subunit composition and role in 40S ribosome biogenesis. [PDF]
Nat Struct Mol BiolSmith EM, Ly J, Haug S, Cheeseman IM.
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