Role of RNase MRP in viral RNA degradation and RNA recombination. [PDF]
J Virol, 2011 Jaag HM, Lu Q, Schmitt ME, Nagy PD.
europepmc +3 more sources
Evidence for further non-coding RNA genes in the fungal rDNA region [PDF]
MycoKeys, 2022 Non-coding RNA (ncRNA) genes play important, but incompletely understood, roles in various cellular processes, notably translation and gene regulation.
Magnus Alm Rosenblad +5 more
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Comparison of mitochondrial and nucleolar RNase MRP reveals identical RNA components with distinct enzymatic activities and protein components. [PDF]
RNA, 2010 Lu Q +3 more
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RNase MRP RNA and human genetic diseases [PDF]
Cell Research, 2006 RNase MRP RNA is the RNA subunit of the RNase mitochondrial RNA processing (MRP) enzyme complex that is involved in multiple cellular RNA processing events. Mutations on RNase MRP RNA gene (RMRP) cause a recessively inherited developmental disorder, cartilage-hair hypoplasia (CHH).
Allison N, Martin, Yong, Li
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A new role for proteins subunits of RNase P: stabilization of the telomerase holoenzyme
Microbial Cell, 2020 RNase P, an RNA-protein complex, is essential for processing tRNAs. Three of the ten protein subunits of Saccharomyces cerevisiae RNase P (and a related complex, RNase MRP) co-purify with yeast telomerase, another RNA-protein complex.
P. Daniela Garcia, Virginia A. Zakian
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Identification of Non-Coding RNAs in the Candida parapsilosis Species Group. [PDF]
PLoS ONE, 2016 The Candida CTG clade is a monophyletic group of fungal species that translates CTG as serine, and includes the pathogens Candida albicans and Candida parapsilosis. Research has typically focused on identifying protein-coding genes in these species. Here,
Paul D Donovan +3 more
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Interactions between subunits of Saccharomyces cerevisiae RNase MRP support a conserved eukaryotic RNase P/MRP architecture [PDF]
Nucleic Acids Research, 2007 Ribonuclease MRP is an endonuclease, related to RNase P, which functions in eukaryotic pre-rRNA processing. In Saccharomyces cerevisiae, RNase MRP comprises an RNA subunit and ten proteins. To improve our understanding of subunit roles and enzyme architecture, we have examined protein-protein and protein-RNA interactions in vitro, complementing ...
Aspinall, Tanya V. +7 more
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Whole-exome re-sequencing in a family quartet identifies POP1 mutations as the cause of a novel skeletal dysplasia. [PDF]
PLoS Genetics, 2011 Recent advances in DNA sequencing have enabled mapping of genes for monogenic traits in families with small pedigrees and even in unrelated cases. We report the identification of disease-causing mutations in a rare, severe, skeletal dysplasia, studying a
Evgeny A Glazov +7 more
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Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP
Nature Communications, 2020 Pop1 and 6 are subunits of RNase P and RNase MRP, which process ribosomal and tRNAs. The authors show that when Pop1 and 6 are impaired, the telomerase subunit Est1 binds telomerase RNA at normal levels, but the binding is unstable.
P. Daniela Garcia +7 more
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Experimental and Molecular Medicine, 2023 Hepatitis B protein x (HBx) has been reported to promote tumorigenesis in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), but the mechanism awaits further investigation.
Jian Yu +11 more
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