Results 61 to 70 of about 3,043 (149)

A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis [PDF]

open access: green, 2021
Nic Roberston   +7 more
openalex   +1 more source

Small Nucleolar RNAs: Biological Functions and Diseases

open access: yesMedComm, Volume 6, Issue 7, July 2025.
The majority of snoRNAs are derived from the intron region of genes, besides to intronic snoRNAs, some snoRNAs are transcribed as independent genes, often by Pol II or III, these snoRNAs are called intergenic snoRNAs. All of these play a role in the occurrence and progression of various diseases through multiple functions.
Yi Wang   +4 more
wiley   +1 more source

Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1

open access: yesPlant, Cell &Environment, Volume 48, Issue 6, Page 4227-4244, June 2025.
ABSTRACT Decapping 5′‐3′ exoribonucleases from the DXO/Rai1 family are highly conserved among eukaryotes and exhibit diverse enzymatic activities depending on the organism. The biochemical and structural properties of the plant DXO1 differ from the yeast and animal counterparts, which is reflected in the in vivo functions of this enzyme.
Monika Zakrzewska‐Placzek   +5 more
wiley   +1 more source

Introduction. RNase MRP/RNase P systems - [PDF]

open access: yes, 1996
Contains fulltext : 29698___.PDF (Publisher’s version ) (Open Access)
Karwan, R., Pluk, H., Venrooij, W.J. van
openaire  

Folate‐Associated Gene Expression in Primary Tumors Is Associated With Tumor Response and Progression‐Free Survival of Patients With Metastatic Colorectal Cancer Undergoing 5‐FU/Leucovorin‐Based Combination Chemotherapy

open access: yesCancer Medicine, Volume 14, Issue 9, May 2025.
ABSTRACT Background 5‐Fluorouracil (5‐FU) and the Folate Leucovorin (LV) form the chemotherapy backbone for metastatic colorectal cancer (mCRC). Tumoral expression of specific folate‐associated genes is associated with the risk of recurrence in stage III CRC following adjuvant 5‐FU/LV (FLV)‐based combination chemotherapy according to the Nordic bolus ...
Elisabeth Odin   +7 more
wiley   +1 more source

hPop1: an autoantigenic protein subunit shared by the human RNase P and RNase MRP ribonucleoproteins. [PDF]

open access: yesThe EMBO Journal, 1996
The eukaryotic endonucleases RNase P and RNase MRP require both RNA and protein subunits for function. Even though the human RNase P and MRP RNAs were previously characterized, the protein composition of the particles remains unknown. We have identified a human a Caenorhabditis elegans sequence showing homology to yPop1, a protein subunit of the yeast ...
Lygerou, Z.   +3 more
openaire   +3 more sources

RNA‐seq analysis of mitochondria‐related genes regulated by AMPK in the human trophoblast cell line BeWo

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 4, Page 649-661, April 2025.
Using RNA‐seq and other bioinformatics analyses, three clusters of mitochondria related genes, including aldo‐keto reductase family 1 members B10 and B15 (AKR1B10, AKR1B15), alanyl‐tRNA synthetase 1 (AARS1), mitochondrial ribosomal protein S6 (MRPS6), mitochondrial calcium uniporter dominant negative subunit beta (MCUB) and dihydrolipoamide branched ...
Bin Wu   +6 more
wiley   +1 more source

Thermally Triggered Double Emulsion‐Integrated Hydrogel Microparticles for Multiplexed Molecular Diagnostics

open access: yesAdvanced Science, Volume 12, Issue 12, March 27, 2025.
This paper presents the development of a multiplexed RT‐qPCR using a double emulsion (DE)‐based carrier and hydrogel microparticle reactor, termed TaqPIN. The DE, enhanced by a hydrogel network, securely stores nucleic acid reagents until heating releases them for reaction.
Eui Ju Jeon   +14 more
wiley   +1 more source

MicroRNA750-3p Targets Processing of Precursor 7 to Suppress Rice Black-Streaked Dwarf Virus Propagation in Vector Laodelphax striatellus

open access: yesViruses
MicroRNAs (miRNAs) are non-coding RNAs, which, as members of the RNA interference pathway, play a pivotal role in antiviral infection. Almost 80% of plant viruses are transmitted by insect vectors; however, little is known about the interaction of the ...
Haitao Wang   +5 more
doaj   +1 more source

Regulation of Shade Avoidance Under Low‐Blue‐Light by MTA in Soybean

open access: yesAdvanced Science, Volume 12, Issue 5, February 3, 2025.
This study explores the role of N6‐methyladenosine (m6A) in shade avoidance in soybean. By generating double mutants impaired in m6A writer genes, researchers found that m6A regulates shade avoidance response and shade resistance by altering the expression of blue light signaling genes, offering insights into plant adaptation to changing light ...
Liya Zhang   +10 more
wiley   +1 more source

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