Biomolecules, 2016 RNase P, the essential activity that performs the 5′ maturation of tRNA precursors, can be achieved either by ribonucleoproteins containing a ribozyme present in the three domains of life or by protein-only enzymes called protein-only RNase P (PRORP ...
Cédric Schelcher +2 more
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The rice RNase P protein subunit Rpp30 confers broad-spectrum resistance to fungal and bacterial pathogens. [PDF]
Plant Biotechnol J, 2021 Summary RNase P functions either as a catalytic ribonucleoprotein (RNP) or as an RNA‐free polypeptide to catalyse RNA processing, primarily tRNA 5′ maturation.
Li W +9 more
europepmc +2 more sources
Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P. [PDF]
Nat Commun, 2022 Li Y +14 more
europepmc +2 more sources
Application of human RNase P normalization for the realistic estimation of SARS-CoV-2 viral load in wastewater: A perspective from Qatar wastewater surveillance. [PDF]
Environ Technol Innov, 2022 El-Malah SS +12 more
europepmc +2 more sources
Molecular insights into HSD10 disease: impact of SDR5C1 mutations on the human mitochondrial RNase P complex [PDF]
Nucleic Acids Research, 2015 SDR5C1 is an amino and fatty acid dehydrogenase / reductase, moonlighting as a component of human mitochondrial RNase P, which is the enzyme removing 5 (cid:2) -extensions of tRNAs, an early and crucial step in tRNA maturation.
Elisa Vilardo, Walter Rossmanith
semanticscholar +3 more sources
The discovery of a catalytic RNA within RNase P and its legacy. [PDF]
J Biol ChemKirsebom LA, Liu F, McClain WH.
europepmc +3 more sources
A novel experimental approach for the selective isolation and characterization of human RNase MRP
RNA Biology, 2022 RNase MRP is a ribonucleoprotein complex involved in the endoribonucleolytic cleavage of different RNAs. Mutations in the RNA component of the RNP are the cause of cartilage hair hypoplasia.
Merel Derksen +5 more
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RNA Biology, 2009 Ribonuclease P (RNase P) is a ribonucleoprotein comprised of a catalytic RNA subunit and one or several protein subunits. RNase P is best known for its role in 5'-processing of tRNA precursors. RNase P enzymes from almost all forms of life, including protein-synthesizing organelles, contain an RNase P with a conserved, homologous RNA.
J Christopher, Ellis, James W, Brown
openaire +2 more sources
The Bacillus subtilis RNase P holoenzyme contains two RNase P RNA and two RNase P protein subunits [PDF]
RNA, 2001 Ribonuclease P (RNase P) catalyzes the 5' maturation of precursor tRNA transcripts and, in bacteria, is composed of a catalytic RNA and a protein. We investigated the oligomerization state and the shape of the RNA alone and the holoenzyme of Bacillus subtilis RNase P in the absence of substrate by synchrotron small-angle X-ray scattering and affinity ...
X W, Fang +7 more
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Human RNase P ribonucleoprotein is required for formation of initiation complexes of RNA polymerase III [PDF]
Nucleic Acids Research, 2015 Human RNase P is implicated in transcription of small non-coding RNA genes by RNA polymerase III (Pol III), but the precise role of this ribonucleoprotein therein remains unknown.
Raphael Serruya +6 more
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