Results 31 to 40 of about 455,663 (298)
Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP
Nature Communications, 2020 Ribozyme-based RNase MRP is an essential eukaryotic enzyme involved in the maturation of rRNA and is evolutionarily related to RNase P. Here, the authors present the 3.0 Å cryo-EM structure of the S.
Anna Perederina +6 more
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Influence of Conformation of M. tuberculosis RNase P Protein Subunit on Its Function. [PDF]
PLoS ONE, 2016 RNase P is an essential enzyme that processes 5' end leader sequence of pre-tRNA to generate mature tRNA. The bacterial RNase Ps contain a RNA subunit and one protein subunit, where the RNA subunit contains the catalytic activity.
Alla Singh +3 more
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Evolution and thermodynamics of the slow unfolding of hyperstable monomeric proteins
BMC Evolutionary Biology, 2010 Background The unfolding speed of some hyperthermophilic proteins is dramatically lower than that of their mesostable homologs. Ribonuclease HII from the hyperthermophilic archaeon Thermococcus kodakaraensis (Tk-RNase HII) is stabilized by its remarkably
Koga Yuichi +8 more
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Solution structure of RNase P RNA [PDF]
RNA, 2011 The ribonucleoprotein enzyme ribonuclease P (RNase P) processes tRNAs by cleavage of precursor-tRNAs. RNase P is a ribozyme: The RNA component catalyzes tRNA maturation in vitro without proteins. Remarkable features of RNase P include multiple turnovers in vivo and ability to process diverse substrates.
Alexei V, Kazantsev +5 more
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Human serum RNase-L level is inversely associated with metabolic syndrome and age
Cardiovascular Diabetology, 2017 Background Ribonuclease-L (RNase-L) was known to be a ubiquitous enzyme involved in several cellular functions, especially innate immunity. It was recently shown to participate in adipogenesis in rodents.
Yi-Ting Wang +6 more
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Phosphatidic acid counteracts S-RNase signaling in pollen by stabilizing the actin cytoskeleton [PDF]
, 2018 S-RNase is the female determinant of self-incompatibility (SI) in pear (Pyrus bretschneideri). After translocation to the pollen tube, S-RNase degrades rRNA and induces pollen tube death in an S-haplotype-specific manner. In this study, we found that the
Chen, Jianqing +7 more
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Is alba an RNase P subunit? [PDF]
RNA Biology, 2007 It has been suggested that Alba, a well-established chromatin protein in Archaea, is also a subunit of the archaeal RNase P holoenzyme, based on the observation that the homolog of this protein in humans has been shown to be associated with RNase P activity.
J Chris, Ellis +2 more
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Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location
BMC Genomics, 2002 Background Members of the ribonuclease III superfamily of double-stranded(ds)-RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells. A human RNase III orthologue has been implicated in
Nicholson Rhonda H +2 more
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Protein synthesis inhibitors and catalytic RNA Effect of puromycin on tRNA precursor processing by the RNA component of Escherichia coli RNase P [PDF]
, 1989 RNase P and ribosomes must interact with similar substrate molecules, tRNA precursors in the case of RNase P and aminoacyl-, peptidyl- or free tRNAs in the case of ribosomes.
Direcció Tècnica d'Urbanisme +1 more
core +1 more source
The catalytic core of RNase P [PDF]
Nucleic Acids Research, 1996 A deletion mutant of the catalytic RNA component of Escherichia coli RNase P missing residues 87-241 retains the ability to interact with the protein component to form a functional catalyst. The deletion of this phylogenetically conserved region significantly increases the Km, indicating that the deleted structures may be important for binding to the ...
C J, Green, R, Rivera-León, B S, Vold
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